ID A0A1U8C5N0_MESAU Unreviewed; 1009 AA.
AC A0A1U8C5N0;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 2.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Sorbin and SH3 domain-containing protein 1 isoform X30 {ECO:0000313|RefSeq:XP_012971083.2};
GN Name=Sorbs1 {ECO:0000313|RefSeq:XP_012971083.2};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_012971083.2};
RN [1] {ECO:0000313|RefSeq:XP_012971083.2}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=26319212;
RA Ying B., Toth K., Spencer J.F., Aurora R., Wold W.S.;
RT "Transcriptome sequencing and development of an expression microarray
RT platform for liver infection in adenovirus type 5-infected Syrian golden
RT hamsters.";
RL Virology 485:305-312(2015).
RN [2] {ECO:0000313|RefSeq:XP_012971083.2}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_012971083.2; XM_013115629.2.
DR AlphaFoldDB; A0A1U8C5N0; -.
DR Proteomes; UP000189706; Unplaced.
DR CDD; cd11919; SH3_Sorbs1_1; 1.
DR CDD; cd11922; SH3_Sorbs1_2; 1.
DR CDD; cd11916; SH3_Sorbs1_3; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR003127; SoHo_dom.
DR InterPro; IPR035606; SORBS1_SH3.
DR InterPro; IPR035610; SORBS1_SH3_1.
DR InterPro; IPR035611; SORBS1_SH3_2.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR14167:SF64; SORBIN AND SH3 DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF07653; SH3_2; 1.
DR Pfam; PF14604; SH3_9; 1.
DR Pfam; PF02208; Sorb; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 3.
DR SMART; SM00459; Sorb; 1.
DR SUPFAM; SSF50044; SH3-domain; 3.
DR PROSITE; PS50002; SH3; 3.
DR PROSITE; PS50831; SOHO; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 234..291
FT /note="SoHo"
FT /evidence="ECO:0000259|PROSITE:PS50831"
FT DOMAIN 473..532
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 547..608
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 948..1009
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 50..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 186..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 275..348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 429..452
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 749..821
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 915..947
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..94
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 132..171
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..237
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 434..448
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 765..794
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 795..811
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 922..947
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1009 AA; 111707 MW; 6B341548CF95207C CRC64;
MSSECDVGSS KAVVNGLAPG SHVQDKATAD PLRARSVSAV KIIPVKTLKS PSGLVLPPDM
DPTKICTGKG TVTLRASSSY RETPSSSPVS PQESPKHESK SDERRLSSSA DANGNAQPSP
LAAKGYRSVH PSLSTDKPQG SPLINEVSSS HIETDSQAFL PTSKPSSAYP STTIVNPTIV
LLQHNREQQK RLSSISDPAS ERRVGEQDSV PTPAELTSPS RAAERRAKDD SRRVVKSAQD
LSDVSMDEVG IPLRNTERSK DWYKTMFKQI HKLNRDDDSD LHSPRYSYSE DTKSPLSVPR
SKSEMNYIDG EKVVKRSATL PLPARSSSLK SSPERNDWEP PDKKVDTRKY RAEPKSIYEY
QPGKSSVLTN EKMSSAISPD VTPEPPGYIY SSNFHAVKRE PDGTPGVLAS LENERQIYKS
VLEGGDIPLQ GLSGLKRPSS SASTKDSESP RHFIPADYLE SAEEFIRRRH DDKEMRPARA
KFDFKAQTLK ELPLQKGDIV YIYKQIDQNW YEGEHHGRVG IFPRTYIELL PPAEKAQPRK
LAPVQVLEYG EAIAKFNFNG DTQVEMSFRK GERITLLRQV DENWYEGRIP GTSRQGIFPI
TYVDVLKRPL VKNPVDYIDL PYSSSPSRST TASPQYTSHS KLIMPAPSSL PHPRRALSPE
MHAITSEWIS LTVGVPGRRS LAMTPPLPPL PEASVYDTDH LALSARVRPS LPLSLPYSSR
SDHSTLRSVV SPLALPSPHK AYSLAPGAQA PLHINGDGGI HTHQEGFSQP PQGNSDRVIS
ELSDAFSSQS KRQSWREDGS YERRAESEAG ERYPGGPKIS KKNCLRPSDV VRCLSSEQRL
SEFHTPDDSQ SFKPLGSPFP AWEAGPPELH RGVEADRKAA QSGVSQEAVC NEIINIAEKS
VHYCSTVSHP LDFHHKVPPS DSKSSLIVSQ QPQAQQRRVT PDRSQTSQDL CSYQALYSYV
PQNDDELELR DGDIVDVMEK CDDGWFVGTS RRTRQFGTFP GNYVKPLYL
//
