ID   A0A1U8CDH0_MESAU        Unreviewed;      1057 AA.
AC   A0A1U8CDH0;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=DENN domain-containing protein 1A isoform X2 {ECO:0000313|RefSeq:XP_012977482.1};
GN   Name=Dennd1a {ECO:0000313|RefSeq:XP_012977482.1};
OS   Mesocricetus auratus (Golden hamster).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Cricetidae; Cricetinae; Mesocricetus.
OX   NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_012977482.1};
RN   [1] {ECO:0000313|RefSeq:XP_012977482.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_012977482.1; XM_013122028.2.
DR   AlphaFoldDB; A0A1U8CDH0; -.
DR   eggNOG; KOG3569; Eukaryota.
DR   OrthoDB; 5398783at2759; -.
DR   Proteomes; UP000189706; Unplaced.
DR   GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.450.200; -; 1.
DR   Gene3D; 3.40.50.11500; -; 1.
DR   Gene3D; 6.10.140.1000; -; 1.
DR   InterPro; IPR001194; cDENN_dom.
DR   InterPro; IPR005112; dDENN_dom.
DR   InterPro; IPR043153; DENN_C.
DR   InterPro; IPR040032; DENND1A/B/C.
DR   InterPro; IPR037516; Tripartite_DENN.
DR   InterPro; IPR005113; uDENN_dom.
DR   PANTHER; PTHR13196; DENN DOMAIN-CONTAINING; 1.
DR   PANTHER; PTHR13196:SF22; DENN DOMAIN-CONTAINING PROTEIN 1A; 1.
DR   Pfam; PF03455; dDENN; 1.
DR   Pfam; PF02141; DENN; 1.
DR   Pfam; PF03456; uDENN; 1.
DR   SMART; SM00801; dDENN; 1.
DR   SMART; SM00799; DENN; 1.
DR   SMART; SM00800; uDENN; 1.
DR   PROSITE; PS50211; DENN; 1.
PE   4: Predicted;
KW   Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW   Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189706}.
FT   DOMAIN          13..378
FT                   /note="UDENN"
FT                   /evidence="ECO:0000259|PROSITE:PS50211"
FT   REGION          448..482
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          577..606
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          688..755
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          981..1057
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        688..745
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        995..1011
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1036..1052
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1057 AA;  116168 MW;  2FB4F04BF75D5400 CRC64;
     MGSRIKQNPE TTFEVYVEVA YPRTGGTLSD PEVQRQFPED YSDQEVLQTL TKFCFPFYVD
     SLTVGQVGQH FTFVLTDIDS RQRFGFCRLS SGAKSCFCIL SYLPWFEVFY KLLNILADYT
     TKQQESQWNE LLETLHRLPI PDPGVSVHLS VHSYFTVPDT RELPSIPENR NLTEYFVAVD
     VNNMLHLYAS MLYERRILII CSKLSTLTAC VHGSAAMLYP MYWQHVYIPV LPPHLLDYCC
     APMPYLIGVH FSLMEKVRNM ALDDVVILNV DTNTLETPFD DLQSLPNDVI TSLKNRLKKV
     STTTGDGVAR AFLKAQAAFF GSYRNALKIE PEEPITFSEE AFVSHYRSGA MRQFLQNATQ
     LQLFKQFIDG RLDLLNSGEG FSDVFEEEIN MSEYAGSDKL YHQWLSTVRK GSGAILNTVK
     TKANPAMKTV YKFAKDHAKM GIKEVKNRLK QKDTAENGCA SSAEEPLPKT MPSPLVEAKD
     PSLREDRRPI TVHFGQVRPP RPHVVKRPKS NITVEGRRTS VPSPEHLVKP FRHYAVFLSE
     DSDEECQREE APSAGFTESF LFSAPFEWPQ PYRTLKESDS AEGDETGSPE QLVQEPRGPI
     PAPPDRAASI DLLEDVFSSL DMEAPLQPLS QAKSLEDLRT PKDLREQPGN FDYQRLGLCR
     SERGLSMAVA LKLPHPYTTL WSLGQDDTAI PSKPSTTSPE KPSALFGTAS QTPQLPHRPQ
     NQNGILSPST KEEAPIQTPG SITIPRPQGR KTPELGIVPP PPTARPAKLQ AAGGPFGDFS
     SEQLQLDRQR QAALSSALVP GLLPSAVPQG PTELLQPLSP APGAAGIGSD SLLALLDPLN
     TTWSGSTIPP HPSNPSVSST LTPQLSFPPT MTPTPFAQPP LNPFVPSMPV APPTMSLGST
     PARPFGTPPA SLGPAYAPSI LLSGSGFYAP HRSQPNLSAL SMPNLFGQTP VGAHASPLQP
     LGPPAVAPPR IRTLPLARSS ARAAEAKQGL ALRPGEPPLL PPRPPQGLEP ALQPSAPTQA
     RDPFEDLLQK TKQDVCPSAA PASTSVEQLR RQWETFE
//