GenomeNet

Database: UniProt
Entry: A0A1U8CU73_MESAU
LinkDB: A0A1U8CU73_MESAU
Original site: A0A1U8CU73_MESAU 
ID   A0A1U8CU73_MESAU        Unreviewed;       395 AA.
AC   A0A1U8CU73;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   08-MAY-2019, entry version 13.
DE   SubName: Full=ATP-sensitive inward rectifier potassium channel 1 isoform X2 {ECO:0000313|RefSeq:XP_012979363.1};
GN   Name=Kcnj1 {ECO:0000313|RefSeq:XP_012979363.1};
OS   Mesocricetus auratus (Golden hamster).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Cricetidae; Cricetinae; Mesocricetus.
OX   NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_012979363.1};
RN   [1] {ECO:0000313|RefSeq:XP_012979363.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (DEC-2018) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   RefSeq; XP_012979363.1; XM_013123909.1.
DR   GeneID; 101830912; -.
DR   CTD; 3758; -.
DR   Proteomes; UP000189706; Genome assembly.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR003268; K_chnl_inward-rec_Kir1.1.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   PANTHER; PTHR11767:SF6; PTHR11767:SF6; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000189706};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609, ECO:0000313|RefSeq:XP_012979363.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     87    109       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    160    184       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       47    189       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      196    367       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   SITE        175    175       Role in the control of polyamine-mediated
FT                                channel gating and in the blocking by
FT                                intracellular magnesium.
FT                                {ECO:0000256|PIRSR:PIRSR005465-1}.
SQ   SEQUENCE   395 AA;  44985 MW;  504523D0B52E40B0 CRC64;
     MPSIPAGVAG LAGLCKIRAL TERMFKHLRK WFVTHIFGRS RQRARLVSKD GRCNIEFGNV
     DAQSRFIFFV DIWTTVLDLK WRYKMTVFIT AFLGSWFLFG LLWYVVAYVH KDLPEFYPPG
     NHTPCVENIN GMTSAFLFSL ETQVTIGYGF RFVTEQCTTA IFLLIFQSIL GVIVNSFMCG
     AILAKISRPK KRAKTITFSK NAVISKRGGK LCLLIRVANL RKSLLIGSHI YGKLLKTTIT
     PEGETIILDQ TNINFIVDAG NENLFFISPL TIYHVIDHNS PFFHMAAETL PQQEFELVVF
     LDGTVESTSA TCQVRTSYVP EEVLWGYRFV PIVSKTKEGK YRVDFHNFGK TVEVETPHCA
     LCLYNEKDAR ARMKRGYDNP NFVLSEVDET DDTQM
//
DBGET integrated database retrieval system