ID A0A1U8D3L3_ALLSI Unreviewed; 788 AA.
AC A0A1U8D3L3;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Protein Jade-1 {ECO:0000256|ARBA:ARBA00040212};
DE AltName: Full=Jade family PHD finger protein 1 {ECO:0000256|ARBA:ARBA00041998};
DE AltName: Full=PHD finger protein 17 {ECO:0000256|ARBA:ARBA00042970};
GN Name=JADE1 {ECO:0000313|RefSeq:XP_025060347.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025060347.1};
RN [1] {ECO:0000313|RefSeq:XP_025060347.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Cytoplasm, cytoskeleton, cilium basal body
CC {ECO:0000256|ARBA:ARBA00004120}.
CC -!- SIMILARITY: Belongs to the JADE family.
CC {ECO:0000256|ARBA:ARBA00038371}.
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DR RefSeq; XP_014375867.1; XM_014520381.1.
DR RefSeq; XP_014375870.1; XM_014520384.1.
DR RefSeq; XP_025060347.1; XM_025204562.1.
DR AlphaFoldDB; A0A1U8D3L3; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0042995; C:cell projection; IEA:UniProtKB-KW.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15671; ePHD_JADE; 1.
DR CDD; cd15679; PHD_JADE1; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR019542; Enhancer_polycomb-like_N.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR039546; Jade-1_PHD.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR PANTHER; PTHR13793:SF79; PROTEIN JADE-1; 1.
DR Pfam; PF10513; EPL1; 1.
DR Pfam; PF13831; PHD_2; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00249; PHD; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 148..198
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 200..314
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT REGION 311..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 531..573
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 616..659
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 687..707
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 737..771
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 311..325
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 551..573
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 616..636
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 788 AA; 90402 MW; 3D7B78B0F76908A0 CRC64;
MKLHDSYQLN PDEYYVLADP WRQEWEKGVQ VPVSPGTIPE PIARVVSETK AVTFTRPRKY
ILSSGSEPPE LGYVDIRTLA DSVCRYDLND VDVAWLELAN EEFKEMGMPE LDEYTMERVM
EEFEQRCYDN MNHAIETEEG LGIEYDEDVV CDVCQSPDGE DGNEMVFCDK CNICVHQACY
GILKVPEGSW LCRTCALGVQ PKCLLCPKKG GAMKPTRSGT KWVHVSCALW IPEVSIGSPE
KMEPITKISH IPSSRWALVC SLCNEKMGAC IQCSVKNCRT AFHVTCAFDR GLEMKTILAE
NDEVKFKSYC PKHSSTKKPE DENFSESTSQ ENENGIRGSS PPTRLEPFHS IETNQEEAHR
VSVRKQKLQQ LEDEFYTFVD FLEVATVLRL PEESVEFLYQ YWKLKRKANF NKPLITPKKD
EEDNLAKREQ DVLFRRLQLF THLRQDLERV RNLTYMVTRR EKIKRSVCKV QEQIFNFYAK
LVEHERVSGV PSSSSPVENM VLFNSPPLGP DAPKIEDLKW HSAFFRKRMG TSLSQSLKKS
HKRDRIRNSS GSDSKSLLKH PSQREGVSNP GSFLNFEKTF TETRIVSAQQ KNGIVMPDHR
KRRDNRFHCE VLKEELKEKP SKHNHKPLRL TELSQRQTEN KRSVNHASGR SASGPRRDIV
PKCNGSLIKI NYNQTVVKVP TTPTSPVKNW GGFRIPKKGE RQQQGEIQEE TCRQNSNYPY
LGMGRVSPKD RVKTKLKTDS ENDGYVPDAE LSDSETEVAE KKCRQQRLSP NSTISRRTDI
IRRSILAS
//
