ID A0A1U8D3W5_MESAU Unreviewed; 387 AA.
AC A0A1U8D3W5;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 2.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Integrin alpha-7-like isoform X1 {ECO:0000313|RefSeq:XP_012982299.2};
GN Name=LOC101842593 {ECO:0000313|RefSeq:XP_012982299.2};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_012982299.2};
RN [1] {ECO:0000313|RefSeq:XP_012982299.2}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=28071753;
RA McCann K.E., Sinkiewicz D.M., Norvelle A., Huhman K.L.;
RT "De novo assembly, annotation, and characterization of the whole brain
RT transcriptome of male and female Syrian hamsters.";
RL Sci. Rep. 7:40472-40472(2017).
RN [2] {ECO:0000313|RefSeq:XP_012982299.2}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR RefSeq; XP_012982299.2; XM_013126845.2.
DR AlphaFoldDB; A0A1U8D3W5; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.930; Bicelle-embedded integrin alpha(iib) transmembrane segment; 1.
DR Gene3D; 2.60.40.1530; ntegrin, alpha v. Chain A, domain 4; 1.
DR InterPro; IPR018184; Integrin_alpha_C_CS.
DR InterPro; IPR048286; Integrin_alpha_Ig-like_3.
DR InterPro; IPR032695; Integrin_dom_sf.
DR PANTHER; PTHR23220; INTEGRIN ALPHA; 1.
DR PANTHER; PTHR23220:SF90; INTEGRIN ALPHA-7; 1.
DR Pfam; PF20806; Integrin_A_Ig_3; 1.
DR SUPFAM; SSF69179; Integrin domains; 1.
DR PROSITE; PS00242; INTEGRIN_ALPHA; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Integrin {ECO:0000256|ARBA:ARBA00023037,
KW ECO:0000313|RefSeq:XP_012982299.2};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 288..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 54..275
FT /note="Integrin alpha third immunoglobulin-like"
FT /evidence="ECO:0000259|Pfam:PF20806"
FT REGION 159..185
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 342..387
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..175
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 346..360
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 387 AA; 43277 MW; 0BD39B1462CE2368 CRC64;
MKRGAQVTFY LLLSTSGITI ETTELEVELL LATISEQELH PVSVRAQVFI ELPLSISGVA
TPQQLFFSGV VKGESAMRSE RDVGSKVKYE ITVSNQGQSL NTLGSAFLNI MWPHEIANGK
WLLYPMRVEL EGGQGPGKKG ICSPRPNILH LDVDSRDRRR RELEQEQREP QEPPEKLEPS
STSWWPVSSA ERKRNVTLDC AQGTAKCVVF SCPLYSFDRV AVLHVWGRLW NSTFLEEYIA
VKSLEVIVRA NITVKSSIKN LLLRDASTTI PVMVYLDPVA VVAEGVPWWV ILLAVLAGLL
VLALLVLLLW KLGFFKRTKH PEAAVPQYHA VKILREDRQQ FKEEKTGTIQ RSNWGSSQWE
GSDAHPILDA DWHPDLGPDG TPVPVTA
//
