ID   A0A1U8D4L0_ALLSI        Unreviewed;       518 AA.
AC   A0A1U8D4L0;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Kelch-like protein 8 isoform X2 {ECO:0000313|RefSeq:XP_014372629.1};
GN   Name=KLHL8 {ECO:0000313|RefSeq:XP_014372629.1};
OS   Alligator sinensis (Chinese alligator).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC   Alligator.
OX   NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_014372629.1};
RN   [1] {ECO:0000313|RefSeq:XP_014372629.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_014372629.1; XM_014517143.2.
DR   AlphaFoldDB; A0A1U8D4L0; -.
DR   GeneID; 102376927; -.
DR   CTD; 57563; -.
DR   OrthoDB; 5472491at2759; -.
DR   Proteomes; UP000189705; Unplaced.
DR   CDD; cd18448; BACK_KLHL8; 1.
DR   CDD; cd18238; BTB_POZ_KLHL8; 1.
DR   Gene3D; 1.25.40.420; -; 1.
DR   Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR   InterPro; IPR011705; BACK.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR   PANTHER; PTHR24412:SF480; KELCH-LIKE PROTEIN 8; 1.
DR   Pfam; PF07707; BACK; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF01344; Kelch_1; 4.
DR   SMART; SM00875; BACK; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00612; Kelch; 4.
DR   SUPFAM; SSF117281; Kelch motif; 1.
DR   SUPFAM; SSF54695; POZ domain; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   4: Predicted;
KW   Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          64..131
FT                   /note="BTB"
FT                   /evidence="ECO:0000259|PROSITE:PS50097"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        11..35
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   518 AA;  58339 MW;  0AEDF684C9650D53 CRC64;
     MASESMLPEQ AKTHLIKRKR QQQQQQERSS NSDSEDEIFI FEANEAWKDF HNSLLHFYEA
     GELCDITLKV GSKLISCHKL VLACVIPYFR AMFLSEMAEA KQTLIEIRDF DGDAIEDLVK
     FVYSSRLTLT VDNVQPLLYA ACILQVELVA KACCEYMKLH FHPSNCLAVR TFAESHNRID
     LMDMADRYAC EHFTEVVECE DFVNVSPQHL HKLLSSNDLN IKNEKQVYSA AIKWFLANPQ
     HRTLWLDEIL AQVRLPLLPI CFLMGVVAKE EIVKQNLKCR DLLDEAKNYH LHLSSRAVPD
     FEYSIRTTPR KQTAGVLFCV GGRGGSGDPF RSIECYSINK NNWFFGPEMN SRRRHVGVIS
     VGGKVYAVGG HDGNEHLGSM EVFDPLTNKW MMKASMNTKR RGIALASLGG PIYAIGGLDD
     NTCFGDVERY DIESDRWSGV ASMNTPRGGV GSVALVNYVY AVGGNDGVAS LSSVEKYDPH
     LDKWIEVKEM GQRRAGNGVS ELRGCLYVVV YRNPGQIL
//