ID A0A1U8D5I4_ALLSI Unreviewed; 1397 AA.
AC A0A1U8D5I4;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Tenascin-N {ECO:0000313|RefSeq:XP_014372405.1};
GN Name=TNN {ECO:0000313|RefSeq:XP_014372405.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_014372405.1};
RN [1] {ECO:0000313|RefSeq:XP_014372405.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498}.
CC -!- SIMILARITY: Belongs to the tenascin family.
CC {ECO:0000256|ARBA:ARBA00008673}.
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DR RefSeq; XP_014372405.1; XM_014516919.2.
DR STRING; 38654.A0A1U8D5I4; -.
DR GeneID; 102384165; -.
DR KEGG; asn:102384165; -.
DR CTD; 63923; -.
DR eggNOG; KOG1225; Eukaryota.
DR eggNOG; KOG2579; Eukaryota.
DR InParanoid; A0A1U8D5I4; -.
DR OrthoDB; 4173903at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR CDD; cd00055; EGF_Lam; 1.
DR CDD; cd00063; FN3; 10.
DR CDD; cd00087; FReD; 1.
DR Gene3D; 3.90.215.10; Gamma Fibrinogen, chain A, domain 1; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 10.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR041161; EGF_Tenascin.
DR InterPro; IPR036056; Fibrinogen-like_C.
DR InterPro; IPR014716; Fibrinogen_a/b/g_C_1.
DR InterPro; IPR002181; Fibrinogen_a/b/g_C_dom.
DR InterPro; IPR020837; Fibrinogen_CS.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR002049; LE_dom.
DR NCBIfam; NF040941; GGGWT_bact; 1.
DR PANTHER; PTHR46708; TENASCIN; 1.
DR PANTHER; PTHR46708:SF5; TENASCIN N; 1.
DR Pfam; PF18720; EGF_Tenascin; 2.
DR Pfam; PF00147; Fibrinogen_C; 1.
DR Pfam; PF00041; fn3; 10.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00186; FBG; 1.
DR SMART; SM00060; FN3; 10.
DR SUPFAM; SSF56496; Fibrinogen C-terminal domain-like; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 6.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS00514; FIBRINOGEN_C_1; 1.
DR PROSITE; PS51406; FIBRINOGEN_C_2; 1.
DR PROSITE; PS50853; FN3; 6.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022530}.
FT DOMAIN 275..363
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 364..457
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 544..633
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 720..809
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 895..984
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1071..1164
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1157..1374
FT /note="Fibrinogen C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51406"
FT REGION 1372..1397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1397 AA; 155803 MW; E93764041E2020B3 CRC64;
MRPTISLKNY KMGYWHNISF ILGVLLYSAL QTAALQLPAS QNCTSKGQKI SLSHSYKIDL
PKSSQIQVEE EPLPLRDESH TLPDMGEAEE GKEQNIIFRH NIRVLTPKGD CEALDHLRAL
LERMEKLEKE VMELREACNP QKCCGGGQGI SDCSSHGTFI QEICSCNCDE GWEGSDCSHP
SCPNSCSGNG RCVDGKCICH EPYVGEDCSQ RLCPENCSGN GICNNGVCQC YEEFIGDDCS
EKRCPNDCNG NGFCDTGECY CHDGFVGLDC SQVLTPQNLQ LLKTTEGSLT LSWDEVIDVD
YYLISYYPMG YQTSVKQVRV PKGQLSYEIV GLHPSTTYNI TLRHVKKGIS SDPENLQAST
ALSVVGAIWV TDETGDSLEV EWENPPAEVD YYKLRFRSLP GQGEEEVMVP KSSEPKSRYI
ITGLKPGTVY NITVIYMKDN IEGKPSSVTG RTGIDGPTNL VTDRVTEDTA TISWKGVQAP
IDGYMVSYTT ADGDSKEVAV RKDKSMTTLT GLRPGMEYII YIWAEKGAHQ SKRTSTKAVT
EMDGPTNLVT DRVTEDTATI SWKGVRAPID RYMVNYTSPD GDARELPVGQ DRSVHTLTGL
RPGVEYTIYI WAEKGTQQSK STNTTAVTEI DSPTNLVTDP VTEDTATISW RAVQAPIDRY
MVSYTSPDGD SREMAVGNDR SITTLTGLRP GMEYIIYIWA EKGTQQSKRA DTKALTEIDS
PTNLVTDQVT EDTATISWKQ VQAPIDRYMV SYTSPDGDKR EMAVGKDKSI TTLTGLRPGV
EYIIYIWAEK GTQQSKREDT RAVTEIDSPT NLVADRVTEN TATISWTGVQ APIDRYMVSY
TSLDGDTREM AVGKDRSITL TGLRPGMEYI IYIWAEKGTQ QSKRASTEVL TEIDGPTNLV
THQVTEDTVT ISWKQVQAPI DRYMVSYTSP DGDTREMAVG KDRSITTLTG LKPGVEYIIY
IWAEKGTQQS KRADTRAVTE IDSPINLVTD RVTEDTATIS WQGVQAPIDR YMVRYTLPDE
DAKEMAVGKD KSVTTLTGLR PGMEYIIYIW AEKGAQQSKK ANTKALTEID PPKNLRVSDV
TQSTSIVNWT PPTAQIDGYT LTYQGVDGTS KEVQLGPDDQ RFMLEGLGKG VRYTVYVLAF
KGDRWSRKAS SSFSTIGFLY PYPADCSQMQ QNGNATSGMY TIYLNGDASR PMEVYCDMTT
DGGGWIVFQR RNTGELDFYK RWRNYVEGFG DPTGEFWLGL DKLHSLTSAT PIRYEIRVDL
RTSNESAYAV YDFFQVASSR DRYKLSVGNY RGTAGDALTY HNGWKFTTWD RDNDVALSNC
ALAHRGAWWY KNCHLANLNG KYGETKHSEG VNWEPWKGHE FSIPFTEMKI RPQSSSNEPI
LGRKKRSLAG KRKKTRV
//
