ID A0A1U8DAM3_ALLSI Unreviewed; 794 AA.
AC A0A1U8DAM3;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Sarcosine dehydrogenase, mitochondrial {ECO:0000313|RefSeq:XP_014378287.1};
GN Name=LOC102387705 {ECO:0000313|RefSeq:XP_014378287.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_014378287.1};
RN [1] {ECO:0000313|RefSeq:XP_014378287.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
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DR RefSeq; XP_014378287.1; XM_014522801.2.
DR AlphaFoldDB; A0A1U8DAM3; -.
DR STRING; 38654.A0A1U8DAM3; -.
DR GeneID; 102387705; -.
DR KEGG; asn:102387705; -.
DR eggNOG; KOG2844; Eukaryota.
DR InParanoid; A0A1U8DAM3; -.
DR OrthoDB; 1815533at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR032503; FAO_M.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF9; SARCOSINE DEHYDROGENASE; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF16350; FAO_M; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000189705}.
FT DOMAIN 33..304
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT DOMAIN 307..361
FT /note="FAD dependent oxidoreductase central"
FT /evidence="ECO:0000259|Pfam:PF16350"
FT DOMAIN 365..673
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 699..784
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 794 AA; 88261 MW; 384183EB0B1E8848 CRC64;
MTGQRGNITT QTLTLLDSRA VVSVHLPPKP AWLDEYKRLM SLGKVYGVES YVLSPAETKD
LYPLMNVDDL YGTLYVPKDG TMDPAGTCTT LTRAATARGA LVIENCPVTG IQVRADDFGV
QRVTAVETSY GTIQTPCVVN CAGVWARALG QMAGVSVPLV AMHHAYVVTE RIEGIQVSPS
LLFCAWQQIS RTFLYLRLQG DALSVGGYES NPIFWEEVSD KFAFGLFDLD WDVFMQHIEG
AINRVPALEK TGIKSTVCGP ESFTADHKPL MGEAPEVRGF FLGCGFNSAG MMLGGGCGKE
LAHWIIHGRP EKDMYGYDIR RFHHSLTNNN RWIRERSHES YAKNYSVVFP YDEPLAGRNM
RKDPLHEELL QQGCVFQERH GWERPGWFNT QGAAPILDYD YYGAYDQKPH EAYAYNHLLG
NEYTFDFPPH HNTIKKECLT CRNAVAVFDM SYFGKFYLVG PEASKAADWL FTADISKSPG
STVYTCMLNN RGGVESDLTV SRISPGSQAS LAPAFEGDGY YLAVGGAVAQ HNWSHIMRVL
QDMKFQCKLL DCSEELGMIS IQGPLSRTVL QELLDTDLSN EAFPFSSHKL AKAAGCMVRA
MRLSFVGEMG WELHVPKGDC VRVYQAVMKA GAQHGIANAG YRAIDSLSIE KGYRHWHADL
RPDDTPLEAG LAFTCKLKSG IRFLGREALE AQKATGVSRR LVCFTVEEKV PLFGLEAIWR
NGQVVGHIRR ADFGFAINKT IAYGYIRNLD GGPVSLEYVK GGDYMLERMG VTYPARAHTK
SPFDPENKRV KGIY
//
