ID A0A1U8DBE2_ALLSI Unreviewed; 799 AA.
AC A0A1U8DBE2;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Metastasis suppressor protein 1 isoform X3 {ECO:0000313|RefSeq:XP_014377666.1};
GN Name=MTSS1 {ECO:0000313|RefSeq:XP_014377666.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_014377666.1};
RN [1] {ECO:0000313|RefSeq:XP_014377666.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_014377666.1; XM_014522180.2.
DR AlphaFoldDB; A0A1U8DBE2; -.
DR GeneID; 102385780; -.
DR CTD; 9788; -.
DR eggNOG; ENOG502QRG4; Eukaryota.
DR OrthoDB; 3875239at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0007009; P:plasma membrane organization; IEA:InterPro.
DR CDD; cd07643; I-BAR_IMD_MIM; 1.
DR CDD; cd22060; WH2_MTSS1; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR013606; I-BAR_dom.
DR InterPro; IPR030127; MTSS1/MTSS2.
DR InterPro; IPR003124; WH2_dom.
DR PANTHER; PTHR15708; ACTIN BUNDLING/MISSING IN METASTASIS-RELATED; 1.
DR PANTHER; PTHR15708:SF10; PROTEIN MTSS 1; 1.
DR Pfam; PF08397; IMD; 1.
DR Pfam; PF02205; WH2; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR PROSITE; PS51338; IMD; 1.
DR PROSITE; PS51082; WH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000189705}.
FT DOMAIN 1..254
FT /note="IMD"
FT /evidence="ECO:0000259|PROSITE:PS51338"
FT DOMAIN 771..788
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT REGION 259..353
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 428..483
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 510..529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 639..799
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 259..310
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..353
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 702..733
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 799 AA; 86495 MW; 601947D784BC88C9 CRC64;
MEAVIEKECS ALGGLFQTII SDMKGSYPAW EDFINKAGKL QSQLRTTVVA AAAFLDAFQK
VADMATNTRG GTREIGSALT RMCMRHRSIE SKLRQFSSAL IDCLINPLQE QMEEWKKVAN
QLDKDHAKEY KKARQEIKKK SSDTLKLQKK AKKAEALGRG DIQPQLDSAL QDVNDKYLLL
EETEKQAVRK ALIEERGRFC TFVSMLRPVI EEEISMLGEI THLQTISDDL KSLTMDPHKL
PSSSEQVILD LKGSDYSWSY QTPPSSPSTT MSRKSSVCSS NLPQQAPMRL SSVSSHDSGF
MSQDAFQSKS PSPMPPEAPN QNSSSSASSE ASETCQSVSE CSSPTSVSSG STTGAWASTE
KLYNGFYHCS LPSDPSVASF GAGSFPHYLP ASRAWSRASS ALHPDYVHYY TIGPGMLPSS
KIPSWKDWSK PGPYDQPTAN TLQRRKEKRE PDPNGGAQSG PLLPTEEAQR PRSMTVSAAA
RQGEEMEACE ELALALTRGL QLDTQRSSRD SLQCSSGYST QTTTPCCSED TIPSQELAGS
KEGLSRIPFL LHQQNCGLSL DQLHLGKSVK VSDYDYFSVS GDQEAEQQEF DKSSTIPRNS
DISQSYRRMF QAKRPASTAG LPTTLGPVIV TPGVATIRRT PSTKPSVRRG TIGAGPIPIK
TPVIPVKTPT VPDVPGGLPG TLAGAEEPAE QSPESPLADG GQGAMPSSSW SGQASVNPPP
PSQKLSTTDE QRQAVPESEG EESEKESSSM LAPPCQPQSD LGDMSPGDAP QGEDMLNAIR
RGVKLKKTTT NDRSAPRIS
//
