ID   A0A1U8DHV8_ALLSI        Unreviewed;       429 AA.
AC   A0A1U8DHV8;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Xaa-Pro aminopeptidase 3 isoform X3 {ECO:0000313|RefSeq:XP_025064731.1, ECO:0000313|RefSeq:XP_025064732.1};
GN   Name=XPNPEP3 {ECO:0000313|RefSeq:XP_025064731.1,
GN   ECO:0000313|RefSeq:XP_025064732.1};
OS   Alligator sinensis (Chinese alligator).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC   Alligator.
OX   NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025064731.1};
RN   [1] {ECO:0000313|RefSeq:XP_025064731.1, ECO:0000313|RefSeq:XP_025064732.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000256|ARBA:ARBA00001936};
CC   -!- SIMILARITY: Belongs to the peptidase M24B family.
CC       {ECO:0000256|ARBA:ARBA00008766}.
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DR   RefSeq; XP_014377293.1; XM_014521807.1.
DR   RefSeq; XP_014377294.1; XM_014521808.1.
DR   RefSeq; XP_025064731.1; XM_025208946.1.
DR   RefSeq; XP_025064732.1; XM_025208947.1.
DR   Proteomes; UP000189705; Unplaced.
DR   GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR   GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR   CDD; cd01087; Prolidase; 1.
DR   Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR   Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 1.
DR   InterPro; IPR007865; Aminopep_P_N.
DR   InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR   InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR   InterPro; IPR000994; Pept_M24.
DR   PANTHER; PTHR43226; XAA-PRO AMINOPEPTIDASE 3; 1.
DR   PANTHER; PTHR43226:SF4; XAA-PRO AMINOPEPTIDASE 3; 1.
DR   Pfam; PF05195; AMP_N; 1.
DR   Pfam; PF00557; Peptidase_M24; 1.
DR   SMART; SM01011; AMP_N; 1.
DR   SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR   SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE   3: Inferred from homology;
KW   Aminopeptidase {ECO:0000313|RefSeq:XP_025064731.1,
KW   ECO:0000313|RefSeq:XP_025064732.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Manganese {ECO:0000256|ARBA:ARBA00023211};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Protease {ECO:0000313|RefSeq:XP_025064731.1,
KW   ECO:0000313|RefSeq:XP_025064732.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189705}.
FT   DOMAIN          4..133
FT                   /note="Aminopeptidase P N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01011"
SQ   SEQUENCE   429 AA;  48277 MW;  2B58B4576F58EF09 CRC64;
     MSSIQKEAKD WGGMDHTVIL LSNPTYYMSN DIPYTFHQDT NFLYLCGFQE PDSILVLQSL
     PGKVLPSHKA MLFVPRRDLN RELWDGPRSG TDGAVALTGV DEAYTIEEFR NLVAKLKGES
     NVVWYDYARP VHPQLHSEYL QPLTEMKTGS KNRIRGFCHL VQNLRLIKSS AEIERMKVVG
     RVTSQAFTET MFASKSPVDE AFLYAKFEFE CRARGADILA YPPVVAGGNR SNTLHYVKNN
     QLIKDGEMVL LDGGCESSCY VSDITRTWPI NGRFTGPQAE LYQAVLEVQK SCLSLCSPGV
     SLENIYNLML SLTGQKLREL GVLRRSIDEN HFFKAVRKYC PHHVGHYLGM DVHDTPSMSR
     SLPLQPGMVI TIEPGIYIPE DDLAAPKRFR GIGIRIEDDV VVTEDTPLIL SADCPKEIYH
     IEQICGHSL
//