ID A0A1U8DS26_CAPAN Unreviewed; 843 AA.
AC A0A1U8DS26; A0A1U8DUH5;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Elongation factor 2 {ECO:0000313|EMBL:PHT74217.1};
GN ORFNames=T459_21494 {ECO:0000313|EMBL:PHT74217.1};
OS Capsicum annuum (Capsicum pepper).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Capsiceae; Capsicum.
OX NCBI_TaxID=4072 {ECO:0000313|EMBL:PHT74217.1, ECO:0000313|Proteomes:UP000222542};
RN [1] {ECO:0000313|EMBL:PHT74217.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24441736; DOI=10.1038/ng.2877;
RA Kim S., Park M., Yeom S.I., Kim Y.M., Lee J.M., Lee H.A., Seo E., Choi J.,
RA Cheong K., Kim K.T., Jung K., Lee G.W., Oh S.K., Bae C., Kim S.B.,
RA Lee H.Y., Kim S.Y., Kim M.S., Kang B.C., Jo Y.D., Yang H.B., Jeong H.J.,
RA Kang W.H., Kwon J.K., Shin C., Lim J.Y., Park J.H., Huh J.H., Kim J.S.,
RA Kim B.D., Cohen O., Paran I., Suh M.C., Lee S.B., Kim Y.K., Shin Y.,
RA Noh S.J., Park J., Seo Y.S., Kwon S.Y., Kim H.A., Park J.M., Kim H.J.,
RA Choi S.B., Bosland P.W., Reeves G., Jo S.H., Lee B.W., Cho H.T., Choi H.S.,
RA Lee M.S., Yu Y., Do Choi Y., Park B.S., van Deynze A., Ashrafi H., Hill T.,
RA Kim W.T., Pai H.S., Ahn H.K., Yeam I., Giovannoni J.J., Rose J.K.,
RA Sorensen I., Lee S.J., Kim R.W., Choi I.Y., Choi B.S., Lim J.S., Lee Y.H.,
RA Choi D.;
RT "Genome sequence of the hot pepper provides insights into the evolution of
RT pungency in Capsicum species.";
RL Nat. Genet. 46:270-278(2014).
RN [2] {ECO:0000313|EMBL:PHT74217.1, ECO:0000313|Proteomes:UP000222542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. CM334 {ECO:0000313|Proteomes:UP000222542};
RX PubMed=29089032; DOI=10.1186/s13059-017-1341-9;
RA Kim S., Park J., Yeom S.I., Kim Y.M., Seo E., Kim K.T., Kim M.S., Lee J.M.,
RA Cheong K., Shin H.S., Kim S.B., Han K., Lee J., Park M., Lee H.A.,
RA Lee H.Y., Lee Y., Oh S., Lee J.H., Choi E., Choi E., Lee S.E., Jeon J.,
RA Kim H., Choi G., Song H., Lee J., Lee S.C., Kwon J.K., Lee H.Y., Koo N.,
RA Hong Y., Kim R.W., Kang W.H., Huh J.H., Kang B.C., Yang T.J., Lee Y.H.,
RA Bennetzen J.L., Choi D.;
RT "New reference genome sequences of hot pepper reveal the massive evolution
RT of plant disease-resistance genes by retroduplication.";
RL Genome Biol. 18:R210.1-R210.11(2017).
RN [3] {ECO:0000313|EMBL:WMP39879.1}
RP NUCLEOTIDE SEQUENCE.
RA Li W.;
RL Submitted (AUG-2021) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:WMP39879.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=35481627;
RA Wang L., Liu X., Li Q., Xu N., He C.;
RT "A lineage-specific arginine in POS1 is required for fruit size control in
RT Physaleae (Solanaceae) via gene co-option.";
RL Plant J. 111:183-204(2022).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; AYRZ02000008; PHT74217.1; -; Genomic_DNA.
DR EMBL; MZ826544; WMP39879.1; -; mRNA.
DR RefSeq; XP_016537811.1; XM_016682325.1.
DR RefSeq; XP_016537812.1; XM_016682326.1.
DR AlphaFoldDB; A0A1U8DS26; -.
DR STRING; 4072.A0A1U8DS26; -.
DR EnsemblPlants; PHT74217; PHT74217; T459_21494.
DR GeneID; 107839000; -.
DR Gramene; PHT74217; PHT74217; T459_21494.
DR KEGG; cann:107839000; -.
DR OMA; EEDHANI; -.
DR OrthoDB; 166721at2759; -.
DR Proteomes; UP000222542; Chromosome 8.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:1990904; C:ribonucleoprotein complex; IBA:GO_Central.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR GO; GO:0043022; F:ribosome binding; IBA:GO_Central.
DR GO; GO:0003746; F:translation elongation factor activity; IBA:GO_Central.
DR GO; GO:0006414; P:translational elongation; IBA:GO_Central.
DR CDD; cd01681; aeEF2_snRNP_like_IV; 1.
DR CDD; cd04096; eEF2_snRNP_like_C; 1.
DR CDD; cd01885; EF2; 1.
DR CDD; cd16268; EF2_II; 1.
DR CDD; cd16261; EF2_snRNP_III; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42908:SF10; ELONGATION FACTOR 2; 1.
DR PANTHER; PTHR42908; TRANSLATION ELONGATION FACTOR-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF03764; EFG_IV; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 2: Evidence at transcript level;
KW Elongation factor {ECO:0000313|EMBL:PHT74217.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000222542}.
FT DOMAIN 17..344
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 843 AA; 94041 MW; 555C620E38A97BF5 CRC64;
MVKFTAEELR RIMDFKHNIR NMSVIAHVDH GKSTLTDSLV AAAGIIAQEV AGDVRMTDTR
ADEAERGITI KSTGISLYYE MSDDSLKNFK GERNGNEYLI NLIDSPGHVD FSSEVTAALR
ITDGALVVVD CVEGVCVQTE TVLRQALGER IRPVLTVNKM DRCFLELQVD GEEAYQTFQR
VIENANVIMA TYEDPLLGDV QVYPEKGTVA FSAGLHGWAF TLTNFAKMYA SKFGVDESKM
MERLWGENFF DPATKKWTTK STGTASCKRG FVQFCYEPIK QIINTCMNDQ KDKLWPMLQK
LGVTMKSDEK DLMGKALMKR VMQTWLPAST ALLEMMIYHL PSPSTAQKYR VENLYEGPLD
DAYANAIRNC DPEGPLMLYV SKMIPASDKG RFFAFGRVFA GKVSTGMKVR IMGPNYVPGE
KKDLYVKNIQ RTVIWMGKKQ ETVEDVPCGN TVAMVGLDQF ITKNATLTNE KEVDAHPIRA
MKFSVSPVVR VAVQCKVASD LPKLVEGLKR LAKSDPMVVC SIEESGEHII AGAGELHLEI
CLKDLQDDFM GGAEIIKSDP VVSFRETVLE KSSRTVMSKS PNKHNRLYME ARPMEEGLAE
AIDDGRIGPR DDPKVRSKIL AEEFGWDKDL AKKIWCFGPE TTGPNMVVDM CKGVQYLNEI
KDSVVAGFQW ASKEGALAEE NMRGICFEVC DVVLHADAIH RGGGQVIPTA RRVIYASQLT
AKPRLLEPVY LVEIQAPEQA LGGIYSVLNQ KRGHVFEEMQ RPGTPLYNIK AYLPVIESFG
FSGTLRAATS GQAFPQCVFD HWEMMSSDPL ESGSQAQQLI LDIRKRKGLK EQMTPLSEFE
DKL
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