ID A0A1U8DXL5_ALLSI Unreviewed; 591 AA.
AC A0A1U8DXL5;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Kinesin-like protein KIF25 {ECO:0000313|RefSeq:XP_014382439.1};
GN Name=KIF25 {ECO:0000313|RefSeq:XP_014382439.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_014382439.1};
RN [1] {ECO:0000313|RefSeq:XP_014382439.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
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DR RefSeq; XP_014382439.1; XM_014526953.2.
DR AlphaFoldDB; A0A1U8DXL5; -.
DR STRING; 38654.A0A1U8DXL5; -.
DR GeneID; 102373699; -.
DR KEGG; asn:102373699; -.
DR CTD; 3834; -.
DR eggNOG; KOG0239; Eukaryota.
DR InParanoid; A0A1U8DXL5; -.
DR OrthoDB; 453489at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47972:SF66; KINESIN MOTOR DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR47972; KINESIN-LIKE PROTEIN KLP-3; 1.
DR Pfam; PF00225; Kinesin; 2.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Reference proteome {ECO:0000313|Proteomes:UP000189705}.
FT DOMAIN 175..574
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT REGION 449..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 141..168
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 271..278
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 591 AA; 66162 MW; EBE7F0C4CB07DAC8 CRC64;
MRQSGGISLG FVSDQRVRQL ERKLRTKEER IVVLETENSL LHLKLAECQG LIGRSTDEAS
QLYFVSEKQQ NLHKSLPSLV IQELHATIQG LKQDLKNLHS FALERSRDFQ HQYKNHLYQV
LTAVQKIQLQ NEAMQTFQTK AFDLEQSLQE VTERYEKEKR KRRVLHNSLI ELRGNIRVHC
RIRPLLLFDA TPGHSVSHNR HKKLSEKVAY AADDETVLVK CSRPGHASIN KLFQFERVYS
ATESQDAVFA DVAPLLTSLL DGYNVCIMAY GQTGSGKTHT MFGPLSGDNF IFSTEDGPEL
GIIPRATEEV FRLISEKPPG SLWVEVSVVE VYNNEIFDLL AKDSYGTVFG IKREVVTTKE
GKSDVPFLTY ETVENAAEFL QLVNKGLQLR VKHPTLVHAH SSRSHLIVTL TIAMTVLGDS
IGTLWADEES SQKLSKVLSC TFPQQLREDK TTFSSRASSP AHSEPTEKPK HIKTKLQLVD
LAGSECVGMS GVTGAALRET SFINRSLSAL SDVLGAISEQ RSHIPYRNSK LTHLLQDSIG
GDAKLLVMLC VSPCQKYLAE SLQSLGFGTR ARQVQRGQVK KRNPLVSSKS K
//
