ID A0A1U8F7R7_CAPAN Unreviewed; 455 AA.
AC A0A1U8F7R7;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=UDP-glucuronate 4-epimerase 6 {ECO:0000313|EMBL:PHT66860.1};
GN ORFNames=T459_31285 {ECO:0000313|EMBL:PHT66860.1};
OS Capsicum annuum (Capsicum pepper).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Capsiceae; Capsicum.
OX NCBI_TaxID=4072 {ECO:0000313|EMBL:PHT66860.1, ECO:0000313|Proteomes:UP000222542};
RN [1] {ECO:0000313|EMBL:PHT66860.1, ECO:0000313|Proteomes:UP000222542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. CM334 {ECO:0000313|Proteomes:UP000222542};
RX PubMed=29089032; DOI=10.1186/s13059-017-1341-9;
RA Kim S., Park J., Yeom S.I., Kim Y.M., Seo E., Kim K.T., Kim M.S., Lee J.M.,
RA Cheong K., Shin H.S., Kim S.B., Han K., Lee J., Park M., Lee H.A.,
RA Lee H.Y., Lee Y., Oh S., Lee J.H., Choi E., Choi E., Lee S.E., Jeon J.,
RA Kim H., Choi G., Song H., Lee J., Lee S.C., Kwon J.K., Lee H.Y., Koo N.,
RA Hong Y., Kim R.W., Kang W.H., Huh J.H., Kang B.C., Yang T.J., Lee Y.H.,
RA Bennetzen J.L., Choi D.;
RT "New reference genome sequences of hot pepper reveal the massive evolution
RT of plant disease-resistance genes by retroduplication.";
RL Genome Biol. 18:R210.1-R210.11(2017).
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. {ECO:0000256|ARBA:ARBA00007637}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHT66860.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AYRZ02000012; PHT66860.1; -; Genomic_DNA.
DR RefSeq; XP_016552269.1; XM_016696783.1.
DR AlphaFoldDB; A0A1U8F7R7; -.
DR STRING; 4072.A0A1U8F7R7; -.
DR EnsemblPlants; PHT66860; PHT66860; T459_31285.
DR GeneID; 107851696; -.
DR Gramene; PHT66860; PHT66860; T459_31285.
DR KEGG; cann:107851696; -.
DR OMA; TSHHHIH; -.
DR OrthoDB; 5491077at2759; -.
DR Proteomes; UP000222542; Chromosome 12.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43574; EPIMERASE-RELATED; 1.
DR PANTHER; PTHR43574:SF67; UDP-GLUCURONATE 4-EPIMERASE 6-LIKE; 1.
DR Pfam; PF01370; Epimerase; 1.
DR PRINTS; PR01713; NUCEPIMERASE.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius}; NADP {ECO:0000256|ARBA:ARBA00022857};
KW Reference proteome {ECO:0000313|Proteomes:UP000222542};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 32..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 109..346
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 455 AA; 50517 MW; C74DC32EF104BB66 CRC64;
MASSIEVMKL ERYNSYIRKV NSTKLIVASS KLLFRVTLLV ALLLIFFFII NYPPFTSSKN
NNTSHIHHNN NIHITTHNLL SSSIYGGGST WEKQVRHSSM PRRINGLSVL VTGVAGFVGS
HCSLALKKRG DGVLGIDNFN SYYDPSLKRG RQRLLAQHEI FIVDGDINDA ELLTKLFDIV
PFTHVLHLAA QAGVRYAMQN PQSYVQSNIA GFVNLLEMAK LANPQPAIVW ASSSSVYGLN
TNVPFSENDT TDQPASLYAA TKKAGEEIAH TYNHIYGLSL TALRFFTVYG PWGRPDMAYF
FFTKDMVQGK PINVYVTQDG KEVARDFTYI DDIVKGCLGA LDTAERSTGS GGKKRGPAQL
RVYNLGNTSP ISVNKLVTIL ESLLNVKAKK NVIKMPRNGD VPFTHANVTL AKKDFGYKPT
TNLSSGLRKF VKWYVSYYGI QSSKELDSPI DHSQD
//
