ID A0A1U8HGL0_GOSHI Unreviewed; 1064 AA.
AC A0A1U8HGL0;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Calcium-transporting ATPase 1, endoplasmic reticulum-type-like {ECO:0000313|RefSeq:XP_016665210.1};
GN Name=LOC107885955 {ECO:0000313|RefSeq:XP_016665210.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016665210.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016665210.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016665210.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_016665210.1; XM_016809721.1.
DR AlphaFoldDB; A0A1U8HGL0; -.
DR STRING; 3635.A0A1U8HGL0; -.
DR PaxDb; 3635-A0A1U8HGL0; -.
DR GeneID; 107885955; -.
DR KEGG; ghi:107885955; -.
DR OrthoDB; 203629at2759; -.
DR Proteomes; UP000189702; Chromosome 12.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0005388; F:P-type calcium transporter activity; IBA:GO_Central.
DR GO; GO:0070588; P:calcium ion transmembrane transport; IBA:GO_Central.
DR GO; GO:0006874; P:intracellular calcium ion homeostasis; IBA:GO_Central.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C.
DR InterPro; IPR004014; ATPase_P-typ_cation-transptr_N.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01494; ATPase_P-type; 3.
DR PANTHER; PTHR42861; CALCIUM-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR42861:SF4; CALCIUM-TRANSPORTING ATPASE 1, ENDOPLASMIC RETICULUM-TYPE-RELATED; 1.
DR Pfam; PF13246; Cation_ATPase; 1.
DR Pfam; PF00689; Cation_ATPase_C; 1.
DR Pfam; PF00690; Cation_ATPase_N; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR SFLD; SFLDG00002; C1.7:_P-type_atpase_like; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SMART; SM00831; Cation_ATPase_N; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 82..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 325..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 860..888
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 988..1008
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1015..1036
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..99
FT /note="Cation-transporting P-type ATPase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00831"
SQ SEQUENCE 1064 AA; 116964 MW; 7E6DD2AC8CB6B76F CRC64;
MGRGGENYGK RENAGAASFK QETFPAWARD VKQCEEKYQV NRELGLSSAE VEKRRQIYGL
NELLKHKPTS IFQLLLEQFN DTLVRILLAA AIISFVLAWY DGEEGGEKEI TAFVEPLVIF
LILIVNAFVG IWQESSAEKA LEALKEIQSE HADVIRDGKK VSSLPAKELV PGDIVELRVG
DKVPADMRVL NMISSTVRVE QGSLTGESEA VSKTVKVVPE NSDIQGKKCM VFAGTTMVNG
NCICLVTEIG MNTEIGKVHS QIHEASQSDT DTPLKKKLNE FGEVLTMIIG MICILVWLIN
VKYFLSWEYV DGWPTNFKFS FEKCTYYFEI AVALAVAAIP EGLPAVITTC LALGTRKMAQ
KNALVRKLPS VETLGCTTVI CSDKTGTLTT NQMAVSKLVA IGSRSGTLRS FDVEGTTYDP
FDGKILGWPV DGMDSNLEMI AKISAVCNDA GVEQSGRHYV AIGMPTEAAL KVLVEKMELP
EKYASSSAPG DPQPIQGCCH VWNKMVQRIA TLEFDRDRKS MGVILPSSSG NKSLLVKGAV
ENLLERSSFI QLLDGSTVEL DKYSKDLILQ VLREMSTDAL RCLGFAYKEE LPEFATYNGD
EDHPAHQLLL NPSNYSSIES NLIFVGLVGL RDPPRKEVRQ AIEDCKAAGI RVMVITGDNK
NTAEAICREI GVFGYREDIT SRSLTGKEFM DHPDQRNHLR QNGGLLFSRA EPRHKQEIVR
LLKQDGEVVA MTGDGVNDAP ALKLADIGVA MGITGTEVAK EASDMVLADD NFSTIVAAVG
EGRSIYDNMK AFIRYMISSN IGEVASIFLT ADLGIPEGMI PVQLLWVNVV SDGRPATALG
FNPQDTDIMK KPPRRSNDSL ITAWILFRYL VIGSYVGLAT VGVFIIWYTH NTFMGIDLSG
DGHSLVTYSQ LSNWDKCPSW VNFTASPFTA GPQVFNFDTN PCDYFRSGKI KASTLSLSVL
VSIEMFNSLN ALSEDGSLLT MPPWVNPWLL LAMSISFGLH FLILYVPFLA QVFGIVPLSL
NEWLLVLAVA FPVILIDEVL KCIGRCTTGP RYSPATKSIK HKAE
//
