ID A0A1U8HXS7_GOSHI Unreviewed; 1824 AA.
AC A0A1U8HXS7;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Sister chromatid cohesion protein {ECO:0000256|RuleBase:RU364107};
GN Name=LOC107888544 {ECO:0000313|RefSeq:XP_016668179.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016668179.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016668179.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016668179.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU364107}.
CC -!- SIMILARITY: Belongs to the SCC2/Nipped-B family.
CC {ECO:0000256|ARBA:ARBA00009252, ECO:0000256|RuleBase:RU364107}.
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DR RefSeq; XP_016668179.1; XM_016812690.1.
DR STRING; 3635.A0A1U8HXS7; -.
DR PaxDb; 3635-A0A1U8HXS7; -.
DR GeneID; 107888544; -.
DR KEGG; ghi:107888544; -.
DR OrthoDB; 1409889at2759; -.
DR Proteomes; UP000189702; Chromosome 13.
DR GO; GO:0090694; C:Scc2-Scc4 cohesin loading complex; IBA:GO_Central.
DR GO; GO:0003682; F:chromatin binding; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0034087; P:establishment of mitotic sister chromatid cohesion; IBA:GO_Central.
DR GO; GO:0071169; P:establishment of protein localization to chromatin; IBA:GO_Central.
DR GO; GO:0061780; P:mitotic cohesin loading; IEA:InterPro.
DR GO; GO:0010468; P:regulation of gene expression; IEA:InterPro.
DR GO; GO:1990414; P:replication-born double-strand break repair via sister chromatid exchange; IBA:GO_Central.
DR CDD; cd15489; PHD_SF; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR026003; Cohesin_HEAT.
DR InterPro; IPR024986; Nipped-B_C.
DR InterPro; IPR033031; Scc2/Nipped-B.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR21704:SF18; NIPPED-B-LIKE PROTEIN; 1.
DR PANTHER; PTHR21704; NIPPED-B-LIKE PROTEIN DELANGIN SCC2-RELATED; 1.
DR Pfam; PF12765; Cohesin_HEAT; 1.
DR Pfam; PF12830; Nipped-B_C; 1.
DR Pfam; PF00628; PHD; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|RuleBase:RU364107};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364107};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|RuleBase:RU364107};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 668..718
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 139..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 358..387
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1460..1482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1770..1824
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..177
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1460..1475
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1803..1824
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1824 AA; 204311 MW; EDD2936AEE9E9E24 CRC64;
MSNPSSSSWV SDQPGQRLMD MAHCGIGLTN TIHSEVAQCL PLPSLPVFCG ASDLELRLFD
DPAVGASRSL NRPQIIAQAG RIADLLRETD VSYLNLRDEA GSVSHDHLEP LELHAQVLQY
NPAAFEYVTP GLVKGKNSGG AMFERKPSES SAPLIGQFQR ETRSNRNKQT DVVANDMPKS
SSKKPKIKKK ADDTGSSVLP DPTELQDAII GNFRELLEDF CSRAQIPTDD RDEMEWLSLP
VNDVRMLVNE IMSVRAKRLL HLVPVDILVK LLRVLDHQIH RAEGLSIDEC EHQDSDVFSL
VFCALESIHA SLAIMAHNDM PKQLYHEEII ERILEFSRHQ ITDVMSAYDP SYRALHKPSE
NGAVEDDDDE EPDAELGSAS KKRRSTKTAK AKKSALNKVS GAVNAILQKL CTILGLLKDL
LLIEKLSDSC VLQLLKTSFT TFLVDNIQLL QLKAIGLLTG IFYSYTQHRT YIIDEMVQLL
WKLPVSKRAL RAYHLPDEEQ RQIQMITALL IQLVHSSANL PEALKQTSIG SPILEVSVDA
GYLTKCHESV QDTCCHFWTR VLQRLASVKT QEASELKLMI ENLVTDLLTT LNLPEYPAAA
PILEVLCVLL LQNAGLKSKD TSVRAMAIDL LGTIAARLKH DALLNRKDKF WISEELLSGD
DTDRSYPKGA CSICFDGKEE KVLYRCQGCQ RFFHSDCMGV REQEGPNRSW YCQFCMCKKQ
LLVLQSYCES QYKDNEKPKR GRSESSKSSD PITKVEIVQQ MLLNHLQDTA SADDVHLFVR
WCYLCLWYKD GPKSQQNFKY YVSRLRSKAI VRDSGTVSSL FLRDSVKKIA LALGQNNSFS
RGFDKILYLL LVSLRENSPV IRAKALRAVS IIVEVDPEVL GDKRVQVAVE GRFCDSAISV
REAALELVGR HIASHPDVSL KYFEKVAERI KDTGVSVRKR AIKIIRDMCN ADPNFSGFTN
ACIEIISRVS DDESSIQDLV CKTFYEFWFE EPSGMQTQYP GDGSSIPLEV AKKTEQIVET
LRQLPNHQFL VTVIKRNLVL DFFPQSAKAA GINPVSLAAV RRRCEVMCKC LLERILQTEE
TSNVEAEVPT LPYVLALHAF CVVDPSLCMP ASDPSQFVIT LQPYLKSQVD NRVGAQLLES
IIFVIDAVVP LMRKLPPSVG DELKQDLKHM IVRHSFLTVV HACIKCLCSV SRKAGNTGDV
VEYLIQLFFK LLDSRATDNK QQVGRSLFCL GLLIRYGNSL FGGSSSKNID VASSISLFKK
YLQMDDFSIK VRSLQALGFA LIARPEYMLE KDIGKILEAA LAASSNVRLK MQMLQNLLEY
LLDAESQMET DKVSDDQVQY TVEGGHSVPV AAGAGDTNIC GGIVQLYWDN ILGRCLDFNE
EVRQSALKIV EVVLRQGLVH PITCVPYLIA LETDPLDVNQ KLAHHLLMNM NEKYPAFFES
RLGDGLQLSF IFMRSISGNA HENPNEKSQS KLPGNLKGKS DAGSLTQARL GVSRIYKLIR
GNRVARNKFM SSIVRKFDNP SWNDSVIPFL MYCTETLALL PFSSPDEPLY LIYAINRVIQ
VRAGALEANL KILSSNLLQT DAQMMTSNNG IVQPDYSQAA YNHMATLDLN GTFQEPPVVQ
PPFFHMTSID LNGTIQQNFS YQSISDYPPA IETTMHKMAP SEPRSLSKDE IQKIQADVLA
ATALQLLMKL KRHLKIVYSL NDQRCQAFSP TEPIKPGDVL TRQNVPFDIG ETQTTLPSTY
QELVQRYQEY KNALREDAID YSTYTANIKR KRPTPRKGGK AVRTTGGGDE DDDYDEEWTG
GSGVRRMSNS GRKSYNIRSS SRQR
//
