ID A0A1U8I1M7_GOSHI Unreviewed; 1171 AA.
AC A0A1U8I1M7;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Protein STICHEL-like 3 {ECO:0000313|RefSeq:XP_016672142.1};
GN Name=LOC107891761 {ECO:0000313|RefSeq:XP_016672142.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016672142.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016672142.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016672142.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the DnaX/STICHEL family.
CC {ECO:0000256|ARBA:ARBA00006360}.
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DR RefSeq; XP_016672142.1; XM_016816653.1.
DR AlphaFoldDB; A0A1U8I1M7; -.
DR STRING; 3635.A0A1U8I1M7; -.
DR PaxDb; 3635-A0A1U8I1M7; -.
DR GeneID; 107891761; -.
DR KEGG; ghi:107891761; -.
DR OrthoDB; 3675885at2759; -.
DR Proteomes; UP000189702; Chromosome 14.
DR GO; GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
DR GO; GO:0005663; C:DNA replication factor C complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IBA:GO_Central.
DR GO; GO:0006261; P:DNA-templated DNA replication; IBA:GO_Central.
DR CDD; cd18137; HLD_clamp_pol_III_gamma_tau; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR022754; DNA_pol_III_gamma-3.
DR InterPro; IPR012763; DNA_pol_III_sug/sutau_N.
DR InterPro; IPR045085; HLD_clamp_pol_III_gamma_tau.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR02397; dnaX_nterm; 1.
DR PANTHER; PTHR11669:SF46; PROTEIN STICHEL-LIKE 3; 1.
DR PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR Pfam; PF13177; DNA_pol3_delta2; 1.
DR Pfam; PF12169; DNA_pol3_gamma3; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702}.
FT DOMAIN 464..605
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 60..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 120..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 337..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 960..1002
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1057..1076
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 741..768
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 63..78
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 130..171
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 349..363
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 971..986
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1171 AA; 130642 MW; 94E488E303E6AF54 CRC64;
MTRVIGDRIL KDANGDINGH LRNHIHLTNC IHLKNHMHKH SPMLADRSLM RDLMVLRRSR
SLRDPSASPQ SWQSPPVVDL VSKNDDDEGI ERHRDERMLS VSSPPLVNFA NSKVVPVEVN
EGEPAISDHS SKTGTRDSRK IRREEASRRS GRVDLYGENK EPEGFTSRNS GRKDRKSRKQ
KGKQTQGVRL KALSEKLNYP PLDSDDVASS NIHLRGRHFR PEKPSVEPEV SIRGLSRVKR
CKFRGARRAC TASSFREVGG PNELSVASNS FAQGSVYPKY GAEEEEEEKE YDERNVTQTP
NCGIPFNWSR IHHRGKSFLD IAGRHFSCGL SDTKLRKGGA GPNGRNVTGM PVESDQSSSS
AKPNAEVLPL LVEASGSQDS AANAGWSNDY SGELGIFADN LLKRNVDSDL ASEAGYGDKR
KLSRNLHGRH QNLTQKYIPR TFRDLVGQNL VSQALSNAVV RRKVGLLYIF YGPHGTGKTS
CARIFARALN CQSLEQPKPC GFCNSCISHD KGKSQNIREV GPVGNFDFEG IMDQLDNMTI
TRLPSQYRVF IFDDCDSLST DCWSAISKVI DRVPRRIVFI FVSSSLDILP HIIVSRCQKF
FFPKLKDADI IYALQRIASR EDIEIEKDAL KLIASLSDGS LRDAEMTLEQ LSLLGQRISV
PLVQELVGLI SDEKLVDLLD LALSADTVNT IKSLRVIMET GVEPLALMSQ LATVITDVLA
GSYDFSQERH RRKFFRRQPL SKEDMEKLRQ ALKTLSEAEK QLRMSNDKLT WLTAALLQLA
PDQQYILPIS SSDTSSRHSP LPLNDLGGRE IVRKGGELVE LRNNNTRVLS TNARPENLYA
GSSADFETSI MKGKRHAFAG MAPQSVAENH NGTEGIWLEV LQKIQDDSLK EFLYREGKLI
SVNLGAAPTI RLTFSSQVTK SKAEKFRGHI LQAFESVLGS PVTIEIRCEA KKDVYHGLLD
IPPSGDGPSQ IVMDPESNSR NRMPSASFGD ISKKPMRDSD AGVSPQAQLL HHESLEARRS
EIVVIPTSLR KAKDNEHASN VESNRIDSTV ADAAAYRKST SASTSGRRKA GELSQSHSIV
RSKVSLAHVI QHAEGRKQRN EWSKHNAMSI AEQLEKENLR LEPRSRSLLC WKASRVTRRK
LSRLKTRTRR PHPILKLVLC GKCLSSKSSR R
//
