ID A0A1U8I5Q8_GOSHI Unreviewed; 885 AA.
AC A0A1U8I5Q8;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN Name=LOC107891305 {ECO:0000313|RefSeq:XP_016671543.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016671543.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016671543.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016671543.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_016671543.1; XM_016816054.1.
DR AlphaFoldDB; A0A1U8I5Q8; -.
DR STRING; 3635.A0A1U8I5Q8; -.
DR PaxDb; 3635-A0A1U8I5Q8; -.
DR GeneID; 107891305; -.
DR KEGG; ghi:107891305; -.
DR OrthoDB; 5354890at2759; -.
DR Proteomes; UP000189702; Chromosome 14.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14066; STKc_IRAK; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008266; Tyr_kinase_AS.
DR PANTHER; PTHR48056; LRR RECEPTOR-LIKE SERINE/THREONINE-PROTEIN KINASE-RELATED; 1.
DR PANTHER; PTHR48056:SF40; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 5.
DR Pfam; PF13855; LRR_8; 2.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00369; LRR_TYP; 7.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000313|RefSeq:XP_016671543.1};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Receptor {ECO:0000313|RefSeq:XP_016671543.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000313|RefSeq:XP_016671543.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..885
FT /note="non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010550322"
FT TRANSMEM 532..556
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 604..885
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 885 AA; 97743 MW; 0D27AA739E62D939 CRC64;
MAYLYLSFLL VWFLSKSFLG EAQLNDQATL LAIKEELGGV AGWGDNQTDY CRWEGIRCGL
NHSLVERLDL SRRMLRGNVT LISNLKALKE LDLSYNNFNG RIPSAFGNLS ELEYLDLSLN
KFEGSIPVEL GGLRNLRSLN LSNNFLVGEI PQELEMLAKL QDFQISSNRL NGSIPHWVGR
LTNLRVFTAY ENQLVGKIPD NLGLVSELVL LNLHSNQLDG SIPKSIFAMG KLEILVLTQN
GLTGELPEEV GNCRGLSSVR IGNNKLVGTI PRTIGNDTSL TYFEADNNNL SGEIVSEFAL
CTNLTLLNLA YNGFTGIIPP EIGRLMNLQE LILSGNSLSG DIPRSILGCK NLNKLDLSEN
QFNGTIPNKI CNMTRLQYLL LDQNSFKGEI PHEIGNCVKL LHLQLGNNFF TGSIPPEIGR
IRNLQIALNL SFNRLHGQLP SELGKLDKLV SLDVSSNQLT GNIPPAFKGM LSLIEVNFSN
NFLTGPIPTF VPFQKSPDSS FQANKGLCGE PLSFTCANSD PADYHHTVSY RIILAVIGSG
LAVFVSVSVV VVLFMMRERQ EKAARSVEIE DEETSDQPTI IAGTVFVENL RQAVDLDAVV
KATLKDSNKI NNGTFSTSYK AVMPSGLILS VKRLKSMDRT IVHHQNKMIR ELERLSKLCH
DNLVHPIGFV IYEDVALLLH HYLPNGTLAQ LLHESSKQSE YQPDWPRRLS IAIGVAEGLA
FLHHVAVIHL DISSSNVLLD ADFKPLVGEI EISKLLDPSK GTASISAVAG SFGYIPPEYA
YTMQVTAPGN VYSYGVVLLE ILTTRLPVDE DFGEGVDLVK WVHGARARGE TPEQILDARL
STVSFGWRRE MLAALKVALL CTDTTPAKRP KMKKVVEMLQ EIRQN
//
