ID A0A1U8I7B5_GOSHI Unreviewed; 974 AA.
AC A0A1U8I7B5;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Mannosylglycoprotein endo-beta-mannosidase-like isoform X1 {ECO:0000313|RefSeq:XP_016674106.1};
GN Name=LOC107893587 {ECO:0000313|RefSeq:XP_016674106.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016674106.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016674106.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016674106.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
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DR RefSeq; XP_016674106.1; XM_016818617.1.
DR AlphaFoldDB; A0A1U8I7B5; -.
DR STRING; 3635.A0A1U8I7B5; -.
DR PaxDb; 3635-A0A1U8I7B5; -.
DR GeneID; 107893587; -.
DR KEGG; ghi:107893587; -.
DR OMA; AWPNLHW; -.
DR OrthoDB; 2504097at2759; -.
DR Proteomes; UP000189702; Chromosome 15.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR043534; EBDG/EBM.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR041351; Ig_GlcNase.
DR PANTHER; PTHR43536; MANNOSYLGLYCOPROTEIN ENDO-BETA-MANNOSIDASE; 1.
DR PANTHER; PTHR43536:SF1; MANNOSYLGLYCOPROTEIN ENDO-BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF18368; Ig_GlcNase; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 3.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702}.
FT DOMAIN 208..327
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 896..965
FT /note="Exo-beta-D-glucosaminidase Ig-fold"
FT /evidence="ECO:0000259|Pfam:PF18368"
SQ SEQUENCE 974 AA; 110410 MW; 3245C32B91FC0A66 CRC64;
MAEIGQKTLL DSGWLAARST DVQLTGTQLT TTHPPTSPTS SWMEAVVPGT VLATLVENKV
VGDPFYGLEN ETILDIADSG REYYTFWFFT KFQCKLSGNL DLNFRAINYS AELYLNGHKR
VLPKGMFRRH SLEVTDILNP DGSNLLAVLV HPPDHPGSIP PAGGQGGDHE IGKDVATQYV
EGWDWIAPVR DRNTGIWDEV SISVTGPVKI IDPHLVSSFF DRYTRVYLHA TTELENRSSW
VAECSLNIQV TTELEGSVCL MEHLKTQHVS IPPRARIQYT FPQLFFYKPN LWWPNGMGKQ
SLYNVSITVD VKGHGESDSW GQLFGFRKIE SHIDSATGGR LFKVNGQPIF IRGGNWILSD
CLLRLSKERY KTDIKFHADM NLNMIRCWGG GLAERPEFYH YCDVYGLLVW QEFWITGDVD
GRGVPVSNPN GPLDHDLFML CARDTVKLLR NHPSLGLWVG GNEQVPPADI NTSLKNDLKL
HPFFESQSEN ITSVEGLSTA YKDPSQYLDG TRVYIQGSMW DGFANGKGGF TDGPYEIQNP
EDPFKDNFYK YGFNPEVGSV GIPVAATIRA TMPREGWQIP LFKKLPNGYT EEVPNPIWQY
HKYLPYSKPG KVHDQIELYG TPKDLDDFCL KAQLVNYIQY RALLEGWTSR MWSKYTGVLI
WKTQNPWTGL RGQFYDHLLD QTAGFFGCRC AAEPIHVQLN LATYFIEVVN TTAEELSNVA
IEASVWDLEG ACPYYKVFDK LSLPPKKVVS ISEMKYPKSK NPKPVFFLLL KLYHVSNYSI
VSRNFYWLHV SGGDYKLLEP YRNKRIPLKI TSKTFIKGSS YEVEMKVLNK SKKPDPKTLT
YKNNFAVRND DSDFDMTSLE PIPDTRADLK QPTGLFQRLY RQFSRESDGL RVAEINGSDG
GVAFFLNFSV HGAKMEHEEG EDSRILPVHY SDNYFSLVPG EEMSIKISFK VPPGVSPRVT
LRGWNYHHGV HTVL
//
