ID A0A1U8IG10_GOSHI Unreviewed; 913 AA.
AC A0A1U8IG10;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN Name=LOC107896409 {ECO:0000313|RefSeq:XP_016677065.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016677065.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016677065.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016677065.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
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DR RefSeq; XP_016677065.1; XM_016821576.1.
DR AlphaFoldDB; A0A1U8IG10; -.
DR GeneID; 107896409; -.
DR OrthoDB; 1085273at2759; -.
DR Proteomes; UP000189702; Chromosome 16.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 4.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48056; LRR RECEPTOR-LIKE SERINE/THREONINE-PROTEIN KINASE-RELATED; 1.
DR PANTHER; PTHR48056:SF25; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 8.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00369; LRR_TYP; 7.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000313|RefSeq:XP_016677065.1};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Receptor {ECO:0000313|RefSeq:XP_016677065.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000313|RefSeq:XP_016677065.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..913
FT /note="non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010518949"
FT TRANSMEM 598..620
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 628..908
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 913 AA; 99769 MW; C70CEF7D9E16BAB7 CRC64;
MEISPWSLPF NLLFTSMLIV VVLAADPYSK ALLSLKSEII DGSNSLDDWK VPPGETPSGK
VHACSWSGVK CNKNSTIVVG LNLGMKNLAG ELLGNQLSVF TQLVELNVSQ NAFSGELPVE
IFNLSKLTTF DISGNNFSGR FPNGITGLKK LVVLDALSNS FSGPLPVEVT ELESLKVLNL
AGSYFDAEIP SSYGSFKSLE YLHLAGNSLT GKIPPELGKL KTVTHMEIGY NFYEGSIPWE
LSNMTELQYL DIAGANLSGS IPKQLCNLSK LESLFLFRNQ LMGSIPWEFS QMVSLINLDL
SDNLISGPIP ESFGELKKLK LLSLMFNEMN GTVPDTIAEL PSMETLFIWN NFFTGSLPEN
LGRHSRLRWL DVSNNSFVGS IPPGVCAGGE IPLNFSHLHG IRYIDLSGNR FTGGIPADIS
KALKLQYFSV SNNPELGGTI PWKTWSLPFL QNFSASFCNI SGNLPPFRSC KSLVVVELQK
NTISGSIPNS ISNCQSLEII NLARNHLSDH IPKELASLPS LGVVDLSHND FSGSIPAEFA
KSSSLVLLNV SFNDISGTIP SHELLQSMGS SAYTGNPKLC GAPLQSCSTA IDGKKLRLIL
LISAGVVILI AATVSLLIHL RKGSKGQWKM NSFIGLPQFT ANDVLRSFNA TDSKEELPPF
SGAFCKAVLP TGITVLVKKL EWEPKRVKIA SEFITQLGNS RHMNLIRLLG FCYNNQLTYL
LYDCLPNGNL AEKLRMQRDW GMKCRIIIGI AKGLCFLHHD CNPAIPHGDL KSSNVMFDDN
FEPRLADFGF KHLIQLIKGT VPATSSRLGT GEFNDAIKDE LYKDIYNFGE LILEILTNGK
VIKGGASIQS KPKDVVLREM YDENEAGSTN SLQEDEMKQV VDVALLCTKS RAVDRPSIED
ALKLLSGLKA NGK
//
