ID A0A1U8IUP1_GOSHI Unreviewed; 515 AA.
AC A0A1U8IUP1;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Glycerol-3-phosphate 2-O-acyltransferase 6-like {ECO:0000313|RefSeq:XP_016680133.1};
GN Name=LOC107899048 {ECO:0000313|RefSeq:XP_016680133.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016680133.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016680133.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016680133.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GPAT/DAPAT family.
CC {ECO:0000256|ARBA:ARBA00007937}.
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DR RefSeq; XP_016680133.1; XM_016824644.1.
DR AlphaFoldDB; A0A1U8IUP1; -.
DR STRING; 3635.A0A1U8IUP1; -.
DR PaxDb; 3635-A0A1U8IUP1; -.
DR OrthoDB; 1205979at2759; -.
DR Proteomes; UP000189702; Chromosome 17.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0090447; F:glycerol-3-phosphate 2-O-acyltransferase activity; IBA:GO_Central.
DR GO; GO:0016791; F:phosphatase activity; IBA:GO_Central.
DR GO; GO:0010143; P:cutin biosynthetic process; IBA:GO_Central.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd06551; LPLAT; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR PANTHER; PTHR15486; ANCIENT UBIQUITOUS PROTEIN; 1.
DR PANTHER; PTHR15486:SF49; LIPID DROPLET-REGULATING VLDL ASSEMBLY FACTOR AUP1; 1.
DR Pfam; PF01553; Acyltransferase; 1.
DR Pfam; PF12710; HAD; 1.
DR SMART; SM00563; PlsC; 1.
DR SUPFAM; SSF69593; Glycerol-3-phosphate (1)-acyltransferase; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
PE 3: Inferred from homology;
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023209};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 40..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 301..402
FT /note="Phospholipid/glycerol acyltransferase"
FT /evidence="ECO:0000259|SMART:SM00563"
FT REGION 485..515
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 487..515
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 515 AA; 57399 MW; 72DD26D2CFE841FB CRC64;
MGAHPCFQPV SKCSSEGRSN QTVAADLDGT LLVSRSAFPY YMLIALEAGS LLRALLLLLS
VPVVYSTYLF ISESFAINTF IFISFAGLKI RDIELVSRSV LPKFYADDVH PETWRVFSSF
GKRYIITANP RIMVEPFAKT FLGADKVIGT ELQVTKTGRA TGFTIKPGVL VGEHKRAAIS
KEFGTELPDL GLGDREIDHY FMSLCKEGYM VPRTKCEPLP KTKLLSSVIF HEGRLVQRPT
PLAALLTFLW LPIGFILSLL RVYLNIPLPE RIARYNYMIL GIKLIVKGTP PPAPKKGQSG
VLFVCNHRTV LDPVVTAVAL GRKISCVTYS ISKFTEIISP IKAVALSRER EKDAANIKRL
LEEGDLVICP EGTTCREPFL LRFSALFAEL TDRIVPVAIN ARQTVFHGTT VRGYKLLDPY
FVFMNPMPTY EITFLNQLPA ELTCNGGKPA IEVSNYIQRV LAGTLGFECT NLTRKDKYVM
LAGTDGRVPS KKEKEQEKQK AKGINKKEDQ YPELN
//
