ID A0A1U8IYZ3_GOSHI Unreviewed; 720 AA.
AC A0A1U8IYZ3;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN Name=LOC107901708 {ECO:0000313|RefSeq:XP_016683291.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016683291.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016683291.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016683291.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR RefSeq; XP_016683291.1; XM_016827802.1.
DR AlphaFoldDB; A0A1U8IYZ3; -.
DR STRING; 3635.A0A1U8IYZ3; -.
DR PaxDb; 3635-A0A1U8IYZ3; -.
DR GeneID; 107901708; -.
DR KEGG; ghi:107901708; -.
DR OrthoDB; 5489991at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000189702; Chromosome 18.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd16664; RING-Ubox_PUB; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR045210; RING-Ubox_PUB.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23315; U BOX DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR23315:SF266; U-BOX DOMAIN-CONTAINING PROTEIN 17; 1.
DR Pfam; PF00514; Arm; 1.
DR Pfam; PF04564; U-box; 1.
DR SMART; SM00185; ARM; 4.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50176; ARM_REPEAT; 1.
DR PROSITE; PS51698; U_BOX; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 291..365
FT /note="U-box"
FT /evidence="ECO:0000259|PROSITE:PS51698"
FT REPEAT 436..478
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
SQ SEQUENCE 720 AA; 79206 MW; 6B212DE44E94637A CRC64;
MATAAIFSSL RRRRSPSLEA FLAPVELTQV ALLQTLAAVS SELIYCFSDK PFFFQRRNSR
SLIRKIEIFL VMLEYLRDSG SRSMPNLPST AILCFKELYL LLYRSKILLD YCAQSSKLWL
LLQNHSISGH FHDLNQEIST LLDVFPINDV GLSDDVREQV ELLQKHARKA KLYVDKSDEN
LRLRFFSFLN EFDNGRIPNH VDIRLFFVER LGIRDAKSCR SEIEFLEEQI VNHEGDIEPT
ACVLNGFVAI TRYCRFLLFG FEEDEVQLPS RKQKKPRKGL ITREIADTFV TIPKDFCCPI
SLDLMTDPVI ISTGQTYDRS SIVRWLEEGH CTCPKTGQML IHTRLVPNRA LRNLIMQWCT
AHSVPYDPPE AADAPAESFA EALPIKAATE ANRATTTLLV QHLANGSQGA QAIAAREIRL
LAKTGKKNRA FIAEAGAIPH LCKLLSSSNP VAQENSVTAM LNLSIYDKNK SLIMDEDGCL
RSIVEVLRLG LTTEARENAA ATLFSLSAVH DYKKRIADQG GAIEALAGLL RVGTPRGKKD
AVTALFNLST HSDNYARMIE VGAVTALVGA LGNEGVAEEA AGALALIVRQ PIGAEAVGKE
EMAVAGLITM MRCGTARGKE NAVAALLELC RSGGAAATER VLKAPALAGL LQTLLFTGTK
RARRKAASLA RVFQRCENAS LHFGGLGVGY ALAGNSTPPN RDPRFTDDVS MPMSISVQVL
//
