ID A0A1U8IZZ5_GOSHI Unreviewed; 1109 AA.
AC A0A1U8IZZ5;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Importin-5-like {ECO:0000313|RefSeq:XP_016683687.1};
GN Name=LOC107901999 {ECO:0000313|RefSeq:XP_016683687.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016683687.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016683687.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016683687.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_016683687.1; XM_016828198.1.
DR AlphaFoldDB; A0A1U8IZZ5; -.
DR STRING; 3635.A0A1U8IZZ5; -.
DR PaxDb; 3635-A0A1U8IZZ5; -.
DR GeneID; 107901999; -.
DR KEGG; ghi:107901999; -.
DR OrthoDB; 24319at2759; -.
DR Proteomes; UP000189702; Chromosome 18.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0061608; F:nuclear import signal receptor activity; IBA:GO_Central.
DR GO; GO:0008139; F:nuclear localization sequence binding; IBA:GO_Central.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000357; HEAT.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR040122; Importin_beta.
DR InterPro; IPR041653; Importin_rep_4.
DR InterPro; IPR041389; Importin_rep_6.
DR InterPro; IPR034085; TOG.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR PANTHER; PTHR10527:SF5; IMPORTIN-5 ISOFORM X1; 1.
DR Pfam; PF02985; HEAT; 1.
DR Pfam; PF13513; HEAT_EZ; 2.
DR Pfam; PF18808; Importin_rep_4; 1.
DR Pfam; PF18829; Importin_rep_6; 1.
DR SMART; SM00913; IBN_N; 1.
DR SMART; SM01349; TOG; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50077; HEAT_REPEAT; 2.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 36..108
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|SMART:SM00913"
FT DOMAIN 362..599
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REPEAT 413..451
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 918..950
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
SQ SEQUENCE 1109 AA; 122915 MW; D62E06B81F079A93 CRC64;
MDQQSQLALI LGPDPIPFET LVSHLMSSSN EQRSHAEALF NLCKQSDPDA LCLRLAHLLQ
VCTQPEIRAM AAILLRKLLT RDDSYIWPRL NISTQSSLKS VLLSQIQVET TKNLSKKLCD
TVAELASSIL PENGWPELLP FMFQCVSSDS PKLQESAFLI FAQLSQYIGD VLTPFIKDLH
TVFLRCLSES SNADVKIAAL NAVINFIQCL TSSSDRDRFQ DLLPAMMRTL TEALNNGNEA
TAQEALELLI ELAGTEPRFL RRQLVDVVGS MLQIAEAESL EEGTRHLAIE FVVTLAEARE
RAPGMMRKLP QFISRLFAIL MRMLLDIEDD AAWHTAESED EDAGETSNYS VGQECLDRLA
ISLGGNTIVP VASEQLPAYL AASEWQKHLA ALIALAQIAE GCAKVMIKNL EQVVSMVLNS
FHDSHPRVRW AAINAIGQLS TDLGPDLQNQ YHQRVLPALA GAMDDFQNPR VQAHAASAVL
NFSENCTPEI LTPYLDGIVS KLLVLLQNGK QMVQEGALTA LASVADSSQE HFQKYYDAVM
PYLKAILVNA TDKSNRMLRA KSLECISLVG MAVGKEKFRD DAKQVMEVLM SLQGSQMETD
DPTTSYMLQA WARLCKCLGQ DFLPYMSVVM PPLLQSAQLK PDVTITSADS DNDIEDSDDE
SMETITLGDK RIGIKTSVLE EKATACNMLC CYADELKEGF FPWIDQVAPT LVPLLKFYFH
EEVRKAAVSA MPELLRSAKL AVEKGMAQGR NETCVKQLSD YIIPALVEAL HKEPDTEICA
SMLDALNECI QISGLLLDES QVRSIVDEIK QVITASASRK RERAERAKAE DFDAEEGELI
KEENEQEEEV FDQVGEILGT LVKTFKASFL PFFDELSSYL TPMWGKDKTA EERRIAICIF
DDVAEQCREA AIKYYDTYLP FILEACNDEN PDVRQAAVYG LGVCTEFGGP VFKPLVGEAL
SRLNAVIWHP NALQPENVMA YDNAVSALGK ICLFHRDSID AAQIVPAWLN CLPIKGDLIE
AKVVHEQLCS MVERSDSEVL GPKHQYLPKI VAVFAEVLCG KDLATEQTAS RMLNLLRQLQ
QTLPAATLAS TWSSLQPQQQ LALQSMLSS
//
