ID   A0A1U8J2E2_GOSHI        Unreviewed;       682 AA.
AC   A0A1U8J2E2;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Arogenate dehydrogenase 1, chloroplastic-like {ECO:0000313|RefSeq:XP_016682783.1};
GN   Name=LOC107901339 {ECO:0000313|RefSeq:XP_016682783.1};
OS   Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX   NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016682783.1};
RN   [1] {ECO:0000313|Proteomes:UP000189702}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX   PubMed=25893780; DOI=10.1038/nbt.3208;
RA   Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA   Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA   Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA   Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA   Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT   "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT   provides insights into genome evolution.";
RL   Nat. Biotechnol. 33:524-530(2015).
RN   [2] {ECO:0000313|RefSeq:XP_016682783.1}
RP   IDENTIFICATION.
RC   TISSUE=Leaf {ECO:0000313|RefSeq:XP_016682783.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_016682783.1; XM_016827294.1.
DR   AlphaFoldDB; A0A1U8J2E2; -.
DR   STRING; 3635.A0A1U8J2E2; -.
DR   PaxDb; 3635-A0A1U8J2E2; -.
DR   GeneID; 107901339; -.
DR   KEGG; ghi:107901339; -.
DR   OrthoDB; 35809at2759; -.
DR   Proteomes; UP000189702; Chromosome 18.
DR   GO; GO:0033730; F:arogenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR028939; P5C_Rdtase_cat_N.
DR   InterPro; IPR046826; PDH_N.
DR   InterPro; IPR003099; Prephen_DH.
DR   InterPro; IPR045011; TYRAAT1/2.
DR   PANTHER; PTHR43207:SF8; AROGENATE DEHYDROGENASE 1, CHLOROPLASTIC; 1.
DR   PANTHER; PTHR43207; AROGENATE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF03807; F420_oxidored; 1.
DR   Pfam; PF02153; PDH_N; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR   PROSITE; PS51176; PDH_ADH; 2.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189702}.
FT   DOMAIN          75..354
FT                   /note="Prephenate/arogenate dehydrogenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51176"
FT   DOMAIN          389..668
FT                   /note="Prephenate/arogenate dehydrogenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51176"
SQ   SEQUENCE   682 AA;  76833 MW;  AE36E5AB51691564 CRC64;
     MITHPCFHPS LSKPSLSFLS SSSPPFLQHL SFLPTSPSIT KPVFVHSVKP LHVKCSSTNP
     TSQSHPDHAP PISTLKIAII GFGNYGQFLA KTLVSQGHIV LSHSRSDYSH VAKKLGVSFF
     LNPHDLCEQH PEVILLCTSI ISTEQVLKTL PLQRLKRSTL FVDVLSVKEF ARNLLLDALP
     LDFDIICSHP MFGPQSAKQS WKDLFFVYEK VRIGNEFSRV QRCEQFLGIF QSEGCKMVEM
     SCQEHDKLAA GSQFMTHTVG RVLDMLGLES TPINTKGYET LLDLVENTCR DSFDLYYGLF
     LYNKSALEMV ERLDLAFDAL RNELFGRLHH VVRKQFFENG EKVKSVHDSS YQNGAASAFS
     SNALRSQDVT IPYEFKGKIL ESVDDSSKLK VAIVGFGNFG QFLAKTLARQ GHSVLAYSRT
     DYRDAAQKLG VSFFSDANDL CEEHPEVILL CTSILSTEKV LKSLPFQRLK RSTLFVDVLS
     VKEFPRNLFL QHLPPEFDIL CTHPMFGPES GKNGWNELPF VFDKVRVGND ERRVARCNSF
     LDIFAREGCR MVEMTCAEHD WHAAGSQFIT HTMGRVLEKL QLESTPINTK GYETLLKLVE
     NTAGDSFELY YGLFMYNVNA MEQLERMDFA FESLKKQLFG RLHGVLRKEL FGDSEKLEVL
     QEKSVGKNGA ALSSSPESVK IS
//