ID A0A1U8J5L0_GOSHI Unreviewed; 1164 AA.
AC A0A1U8J5L0;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=LRR receptor-like serine/threonine-protein kinase FLS2 {ECO:0000313|RefSeq:XP_016683493.1, ECO:0000313|RefSeq:XP_016683494.1};
GN Name=LOC107901844 {ECO:0000313|RefSeq:XP_016683493.1,
GN ECO:0000313|RefSeq:XP_016683494.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016683494.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016683493.1, ECO:0000313|RefSeq:XP_016683494.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016683493.1,
RC ECO:0000313|RefSeq:XP_016683494.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
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DR RefSeq; XP_016683493.1; XM_016828004.1.
DR RefSeq; XP_016683494.1; XM_016828005.1.
DR STRING; 3635.A0A1U8J5L0; -.
DR PaxDb; 3635-A0A1U8J5L0; -.
DR GeneID; 107901844; -.
DR KEGG; ghi:107901844; -.
DR OrthoDB; 455055at2759; -.
DR Proteomes; UP000189702; Chromosome 18.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14066; STKc_IRAK; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 6.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48054:SF47; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48054; RECEPTOR KINASE-LIKE PROTEIN XA21; 1.
DR Pfam; PF00560; LRR_1; 13.
DR Pfam; PF13855; LRR_8; 3.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00365; LRR_SD22; 6.
DR SMART; SM00369; LRR_TYP; 15.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|RefSeq:XP_016683493.1,
KW ECO:0000313|RefSeq:XP_016683494.1};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_016683493.1,
KW ECO:0000313|RefSeq:XP_016683494.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000313|RefSeq:XP_016683493.1,
KW ECO:0000313|RefSeq:XP_016683494.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..1164
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010665769"
FT TRANSMEM 802..827
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 864..1152
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 1164 AA; 127772 MW; 030420FE3409D738 CRC64;
MSKCVSLIIV ILCSVLLTVL HAGPSLEVEV EALQAFKRSV THDPLGALAD WTVANHHCNW
SGIACDPYSS QVISISLLDK QLKGEISPFL GNLSSLQVLD LTLNSFSGHI PPQLGLCSQL
TQLILYYNSL SGLFPPEIGN LRNLQMLDLG DNSLNGSIPD SICNCTSLLA LGIIYNNLTG
TIPKDIGNLV NLQMLVAYRN NLEGPIPVSI GMLGALQSLD LSENRLSGVI PPEIGNLSSL
EYLQLFNNSL TGEIPSQLGR CRSLLALELY TNKFIGAIPH ELGNLVQLQT LRLYGNKLNS
TIPPSLFQLK SLTHLGLSEN ELIGTVSDEV GSLTSLQVLT LHSNKLKGEI PSSITNLTNL
TYLSMSYNSL TGRLPQNLGL LYNLKNLSLE VNHLEGSIPP SIANCTHLMY ISLGFNRITG
KIPSGLGQLP NLTRLSVGAN RMSGEIPDDL FNCSNLRLLS IAENNFTGLL KPDIGKLYNL
QVLKASFNSF VGSIPPEIGN LSQLMTLTLA GNGFTGRIPP EISKASLLQG LSLHDNALEG
ALPERLFELK QLTYLDLQHN KITGPIPDAV SELEFLTYLN LNNNKLNGSI PNRMDRLYRL
STLDLSHNHL SGSIPKSMFA GMKMMQLYLN FSYNFLDGRI PDELGMLEMV QAIDISNNNI
SGVIPTTLRG CRNLFSLDLS GNKLSGIISA DAFAQSDMLR SLNLSRNKLD GEIPENLAKL
KHLSSLDLSQ NQLRGHIPES FTNSSSLRHL NLSFNQLEGH VPENGIFKTI NMSSLVGNRA
LCGNTFLGSC SKRSSNRFLK KAIIILSILG SVSVVLTLVL AISFLLWRAK ESNPVKLENP
EPEFTAAVLR RFDKEELENA TSSFSKDNII GASSLSTVYK GQLEDGQLIA VKNLNLHQFS
KESDKSFYRE VKNLSHLRHK NLVKVLGYAW ESEKLKAVIL QYMENGSLES VIHGFMMDLH
IWTLSKRIDL CISVASALGY LHSGYDFPIV HCDLKPSNIL LDGDWVAHVS DFGTARMLDA
HLHDGSSLSS TSAFEGTIGY LAPEFAYMRN VRTKVDVFSF GIVVMEFLTK QRPTGLMEED
GLPVSLRQRV EKSLATGTKG VLQVLDPMLA SNDSNKQMEA VEELFKLALF CTSPNPEERP
NMNEVLSILS KLKANNYENE AIIS
//
