ID A0A1U8J9T0_GOSHI Unreviewed; 1384 AA.
AC A0A1U8J9T0;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Helicase SEN1-like isoform X2 {ECO:0000313|RefSeq:XP_016687085.1};
GN Name=LOC107905041 {ECO:0000313|RefSeq:XP_016687085.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016687085.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016687085.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016687085.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_016687085.1; XM_016831596.1.
DR GeneID; 107905041; -.
DR OrthoDB; 170190at2759; -.
DR Proteomes; UP000189702; Chromosome 19.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR CDD; cd18042; DEXXQc_SETX; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF525; HELICASE SENATAXIN-RELATED; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|RefSeq:XP_016687085.1};
KW Helicase {ECO:0000313|RefSeq:XP_016687085.1};
KW Hydrolase {ECO:0000313|RefSeq:XP_016687085.1};
KW Nucleotide-binding {ECO:0000313|RefSeq:XP_016687085.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702}.
FT DOMAIN 687..1035
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 1042..1239
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 81..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 181..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 298..326
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 396..429
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1282..1340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 89..106
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 195..211
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 298..324
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1305..1331
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1384 AA; 154503 MW; EC8761EE2AEE509B CRC64;
MGSRGRLLFD LNEPPAEDDE ESDRGICIQP QKALPSANPH ATDLFVTSSG SQRIANNHAF
SYASTGSGFQ PFIRPKVSTC PEVGVEPKRT GDQNSNLASS SSRSNISGEI KSQVAASFVS
GSANAQAMER EEGEWSDAEG TADAYGNFCM HEEVKASQEQ GVQELESNAL GVTVESVSAA
ENSHSPLRLE PHLNENKGNS VQISEGDSKG NISIDGQEEP VLVPKQREVK GIEASHALKC
ANNPVKRKID QQKEAMLGKK RNRKTMFLNL EDVKQAGPIK TSTPRRQNFP TPVITRTVKE
VRTNPQSGER AGEKQGQPIN EDQKQVDLPC NDGINPAVEL FDHKSECDGD TSSGLLARPR
RLNSDTELSE AHLPPIPRQS SWKQPDLRQL KNMQFSNRKP APINQSSMDT KMVNKKHLPS
KKTTATSTSY QDTSVERLIR EVTSEKFWHH PEDTDLQCVP GRFESVEDYV RVFEPLLFEE
CRAQLYSTWE ELTESASRDT HIMVRIKNIE RRERGWYDVI VLPANECKWV FKEGDVAVLL
APRPGSVRNK RNSSTIEEDE DTEVNGRVVG TVRRHIPLDT RDPIGAIVHF YVGDSYDSSS
KVDDDHILRK LQPRSLWYLT VLGSLATTQR EYVALHAFCR LNSQMQTAIL KPSPDHFPKY
EQQSPAMPEC FTPNFVDYLH RTFNGPQLAA IQWAATHTAA GTSSGVTKRQ EPWPFTLVQG
PPGTGKTHTV WGMLNVIHLV QYQHYYTSLL KKLAPESYKQ ANESNPDSVA MGSIDEVLQN
MDQNLFRTLP KLCPKPRMLV CAPSNAATDE LLARVLDRGF IDGEMKIYRP DVARVGVDSQ
TRAAQAVSVE RRTEQLLLKN RDEIFGHIQT LKAREAMLSQ QIATLQRELT AAAVTVRSQG
SVGVDPEILL ARDQNRDVLL QNLAAVVESR DKVLVEMSRL LILEAKFRVG SNFNLEEARA
NLEASFANEA EIVFTTVSSS GRKLFSRLTH GFDMVVIDEA AQASEVAVLP PLALGAARCV
LVGDPQQLPA TVISKAAGTL LYSRSLFERF QQAGCPTMLL SVQYRMHPQI RDFPSRYFYQ
GRLIDSECVA NLPDEVYYKD PLLKPYLFYD ITHGRESHRG GSVSYQNVHE AVFCLRLYEY
LQKTLKSLGV PKITVGIITP YKLQLKCLQR EFESVLRTEE GKRDIYINTV DAFQGQERDV
IIMSCVRASS HGVGFVADIR RMNVALTRAR RALWVMGNAS ALVQSDDWAA LIADAKARNC
YMDMDSLPKD FTKDLLPKEF SGPRGLGYSP SQGKASNMRG LRSAGPRHRS LDMHMESRSG
TPSEDEDKSG TTVISRNGNY RPFKSPLDTF LDDFHPSGDK SREAWQYGIL KKQNSAGTMG
KRDS
//
