ID A0A1U8JAL4_GOSHI Unreviewed; 1365 AA.
AC A0A1U8JAL4;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Probable disease resistance protein At4g27220 isoform X2 {ECO:0000313|RefSeq:XP_016685269.1};
GN Name=LOC107903656 {ECO:0000313|RefSeq:XP_016685269.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016685269.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016685269.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016685269.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR RefSeq; XP_016685269.1; XM_016829780.1.
DR OrthoDB; 1218856at2759; -.
DR Proteomes; UP000189702; Chromosome 19.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR33463; NB-ARC DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR33463:SF205; RPP4C3; 1.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52047; RNI-like; 2.
DR PROSITE; PS51450; LRR; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702}.
FT DOMAIN 78..314
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 1365 AA; 156119 MW; 8F1356FE4E63D073 CRC64;
MGTLDEEIQL NKRCLNWCPN WSWRYQLSKK AMKKIQDISE LLDKFGQLGP VGYPASTALP
TIDFLCSKEF VFSKSSETAF YQIIEALKDD NINMIGLWGM GGVGKTTLAR EVGSQAQKLN
LFDKVVITTV SQKPNFERIQ DQIAQYIGFD MKNEQGRRSE QELWLRLKNE PRILIILDDI
WEPINLKEKI GIPIGDDHKG YKVLLTTRRQ QVCQAMDCQN VVQLGCLNDD EAWTLFEKKA
GLDDFSDDSI KIIANQIVKK CEGLPIAIAP LGSALKGKTH HEWQAAYLRL KDRRLTEIED
VNEENAYVCL EASFDYLKNM ETKTCFLLCS LFPEDDEVYV ENLVGYAWGL ELYKGMDSIK
DVRSEVLASI ETLKNSGLLL DCGERHVKMH DVVRQFALWI ASSRKEISFG TVETLPMDES
FKHYTAISFE TDQTDELPKG VGFPYLKLLL HGGNHLMETS SEFFEGMKAL QVCALNHLLI
SLSTFQFHMN LQTLYLIDCK LSDISMLGKL KTLHILSLSR SDITELPTEA GDLENLRLLD
LSYCYELRRI TPNLIQRLSN LEELYLHGCS SLKWATENST KRESYSSLSE LNSLPKLVVI
SLDISSEHLP DGFMFRRLWS FDFCIGIGRY QKSETCPISR SLRINKSVDA CKQLLEDVES
LQLSRVEGHP NLIPSLDLGF RKLTSLDLQR CHSMQCLIDA SKQQVPITAL SNLRKLSLSH
MFHLEEMCNA PQPQGLLQKL EEVIVSDCGE MQVLFPIAEW RSIEQEWPSR YLSLQSLKIV
EIERCNNLKY IFPMSVANSL GQLHTLKIKS CSQLEDIIQD RQVASKCLLQ SLREVSLIDL
PQLKKMDVNG ILLTQSSLQK LKVHNCPQLT HFIISTKIQE LVFGKMTNEQ LSNLLSCKYE
ELEKYQTSSQ HHPLPVCFPN LIRIDILECE SLKSLFPIIV AQGSSKQLNA PNLQTLWIRR
CFGMEEIIQD SQVPTISFQC LREVQVTECN KLKFLFPICV ANSLGQLQTL RIESCFQLQE
IIQRPDVLIS MSQGLERLNE VELINLPQLK GRDRNDIVLT SPSLHVLRVR DCPQLTPFIV
STNIQELSFS EMTEKKQISN VTVPERRGGT SISNFEELFE CPRYNLSSLE RLTLSELTEL
RVIWSGPIQV EHFQNLTQLT VDDCRRLRYI FSPTIARNLP QLWRLYISPC EELEQIIEKD
QTPSQHHFQP ICFPNLSSIT IMNCENLKCL FPITLAHGGL PNLDRLYLIR VAKLEQVFEG
DESNVSKDEE KVMHLHRLTY LQLDDLPNLV SFGPMSYHFV FPSLTDLRVE GCPNITTRFS
VDSEKSVHAK TQASQSVDEI IVEESATAQE TAWPIGSDIE WRKHI
//
