ID A0A1U8JBI0_GOSHI Unreviewed; 556 AA.
AC A0A1U8JBI0;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Kinesin-like protein KIF22 {ECO:0000313|RefSeq:XP_016687671.1};
GN Name=LOC107905520 {ECO:0000313|RefSeq:XP_016687671.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016687671.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016687671.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016687671.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
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DR RefSeq; XP_016687671.1; XM_016832182.1.
DR AlphaFoldDB; A0A1U8JBI0; -.
DR STRING; 3635.A0A1U8JBI0; -.
DR PaxDb; 3635-A0A1U8JBI0; -.
DR Proteomes; UP000189702; Chromosome 19.
DR GO; GO:0005871; C:kinesin complex; IBA:GO_Central.
DR GO; GO:0005874; C:microtubule; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IBA:GO_Central.
DR GO; GO:0008017; F:microtubule binding; IBA:GO_Central.
DR GO; GO:0003777; F:microtubule motor activity; IBA:GO_Central.
DR GO; GO:0007018; P:microtubule-based movement; IBA:GO_Central.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24115:SF1022; KINESIN-LIKE PROTEIN KIN-6; 1.
DR PANTHER; PTHR24115; KINESIN-RELATED; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702}.
FT DOMAIN 83..454
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT REGION 1..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 209..216
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
FT NON_TER 556
FT /evidence="ECO:0000313|RefSeq:XP_016687671.1"
SQ SEQUENCE 556 AA; 62162 MW; A1559FDFBBF7229D CRC64;
METNTTTPCS SSVTVRRNPR RKARDTPLFS TSRLPSQSTS SSDLPQISSF PFQDILSEKI
QQNSPTIITA TSPSLPQHSV LENLKVYLRI RPLVPLKGST KNAGEQYAKS RQKNVWPQNL
SKKNSVKEKK ISKKKSNESC ITVSEDFRSV TLFPPPPLQE TKRIKSEVFE GFSYVFSAES
TQSEVFEKMV NPLVEDFLGG KSGMLAALGP TGSGKTHTVF GSPREPGMVP LTLKRIFKSA
QGCDSQSSRR FYLSIFEICA ERGKVERICD LSSDKPDLST QQSAIKGLLE VPIHDVAEAE
LLIARALLKR STATTNANSQ SSRSQCIINI RGGSEIADVE TDEQSNSAVL SIVDLAGAER
EKRTGNQGAR LAESNFINNT SMVFGLCLRS LFEHQKNPKK ALQKHFQNSL LTRYLRDYLE
GKKRMTLILT VKSGEDDYID ASYLLRQASP YMKIQFTNIE PQPNLLCNKR QLQTTSKAEQ
SKRMKLGNFD ASMMERKIVG HENRLPDEGD LTSCSADLKS STPLKLNSDD LKKERTHQIM
QSFAKALWNI LKQYNE
//
