ID A0A1U8JCP7_GOSHI Unreviewed; 476 AA.
AC A0A1U8JCP7;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Protein transport protein Sec61 subunit alpha-like {ECO:0000313|RefSeq:XP_016688085.1, ECO:0000313|RefSeq:XP_016688086.1};
GN Name=LOC107905829 {ECO:0000313|RefSeq:XP_016688085.1,
GN ECO:0000313|RefSeq:XP_016688086.1, ECO:0000313|RefSeq:XP_016688087.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016688087.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016688085.1, ECO:0000313|RefSeq:XP_016688086.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016688085.1,
RC ECO:0000313|RefSeq:XP_016688086.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Plastid,
CC chloroplast thylakoid membrane {ECO:0000256|ARBA:ARBA00004454}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004454}.
CC -!- SIMILARITY: Belongs to the SecY/SEC61-alpha family.
CC {ECO:0000256|ARBA:ARBA00005751, ECO:0000256|RuleBase:RU004349}.
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DR RefSeq; XP_016688085.1; XM_016832596.1.
DR RefSeq; XP_016688086.1; XM_016832597.1.
DR RefSeq; XP_016688087.1; XM_016832598.1.
DR STRING; 3635.A0A1U8JCP7; -.
DR PaxDb; 3635-A0A1U8JCP7; -.
DR GeneID; 107905829; -.
DR KEGG; ghi:107905829; -.
DR OrthoDB; 166798at2759; -.
DR Proteomes; UP000189702; Chromosome 19.
DR GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005784; C:Sec61 translocon complex; IBA:GO_Central.
DR GO; GO:0008320; F:protein transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0043022; F:ribosome binding; IBA:GO_Central.
DR GO; GO:0005048; F:signal sequence binding; IBA:GO_Central.
DR GO; GO:0031204; P:post-translational protein targeting to membrane, translocation; IBA:GO_Central.
DR GO; GO:0006616; P:SRP-dependent cotranslational protein targeting to membrane, translocation; IBA:GO_Central.
DR Gene3D; 1.10.3370.10; SecY subunit domain; 1.
DR InterPro; IPR002208; SecY/SEC61-alpha.
DR InterPro; IPR030659; SecY_CS.
DR InterPro; IPR023201; SecY_dom_sf.
DR InterPro; IPR019561; Translocon_Sec61/SecY_plug_dom.
DR NCBIfam; TIGR00967; 3a0501s007; 1.
DR PANTHER; PTHR10906; SECY/SEC61-ALPHA FAMILY MEMBER; 1.
DR PANTHER; PTHR10906:SF52; TRANSLOCON SEC61_SECY PLUG DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF10559; Plug_translocon; 1.
DR Pfam; PF00344; SecY; 1.
DR PIRSF; PIRSF004557; SecY; 1.
DR SUPFAM; SSF103491; Preprotein translocase SecY subunit; 1.
DR PROSITE; PS00755; SECY_1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Translocation {ECO:0000256|ARBA:ARBA00023010};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 34..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 148..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 442..460
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 42..76
FT /note="Translocon Sec61/SecY plug"
FT /evidence="ECO:0000259|Pfam:PF10559"
SQ SEQUENCE 476 AA; 52152 MW; 01A7D4C438D50103 CRC64;
MGGGFRVLHL VRPFLSFLPE VQSADRKIPF REKVICTVVS LFIFLVCSQL PLYGIHSTTG
ADPFYWMRVI LASNRGTVME LGITPIVTSG LVMQLLAGSK IIEVDNSVRE DRALLNGAQK
LLGILIAVGE AVAYVLSGMY GSVSQLGVGN AILIIIQLCF AGIIVICLDE LLQKGYGVGS
GISLFIATNI CENIIWKAFS PTTINSGRGA EFEGAVIAMF HLLITRTDKV RALREAFYRQ
NLPNVTNLLA TVLIFLIVIY FQGFRVVLPV RSKNARGQQG SYPIKLFYTS NMPIILQSAL
VSNLYFISQL LYRKYSGNFF VNLLGKWKES EYSGGQFIPV GGLAYYVTAP ASLADMAANP
FHALFYLVFM LSACALFSKT WIEVSGSSAK DVAKQLKEQQ MVMPGHRDSN LQKELNRYIP
TAAAFGGMCI GALTVLADFM GAIGSGTGIL LAVTIIYQYF ETFEKERASE LGFFGL
//
