ID A0A1U8JGQ2_GOSHI Unreviewed; 1324 AA.
AC A0A1U8JGQ2;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Formin-like protein {ECO:0000256|RuleBase:RU361260};
GN Name=LOC107906827 {ECO:0000313|RefSeq:XP_016689436.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016689436.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016689436.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016689436.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the formin-like family. Class-II subfamily.
CC {ECO:0000256|ARBA:ARBA00006468}.
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DR RefSeq; XP_016689436.1; XM_016833947.1.
DR STRING; 3635.A0A1U8JGQ2; -.
DR PaxDb; 3635-A0A1U8JGQ2; -.
DR GeneID; 107906827; -.
DR KEGG; ghi:107906827; -.
DR OrthoDB; 1118745at2759; -.
DR Proteomes; UP000189702; Chromosome 19.
DR GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.1110; -; 1.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR014020; Tensin_C2-dom.
DR PANTHER; PTHR45733; FORMIN-J; 1.
DR PANTHER; PTHR45733:SF8; FORMIN-J; 1.
DR Pfam; PF02181; FH2; 1.
DR Pfam; PF10409; PTEN_C2; 1.
DR SMART; SM00498; FH2; 1.
DR SMART; SM01326; PTEN_C2; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51182; C2_TENSIN; 1.
DR PROSITE; PS51444; FH2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000189702}.
FT DOMAIN 199..338
FT /note="C2 tensin-type"
FT /evidence="ECO:0000259|PROSITE:PS51182"
FT DOMAIN 908..1310
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT REGION 404..429
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 456..485
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 595..917
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 962..985
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1299..1324
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 414..429
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 604..625
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 639..668
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 675..690
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 693..716
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 720..735
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 745..764
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 774..788
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 801..816
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 826..842
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 849..863
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 871..887
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 962..976
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1324 AA; 145804 MW; BF219F9B11E6354B CRC64;
MGLFRKLFFR KPPDGLLEIS ERVYLFDCCF STDIREEKEY RVYIENIVCK LRDHFTDASF
MVFNFREGEY QSQIASILSE YDMTVMDYPR QYEGCPLLTT ELIHHFLKSS ENWFSLGQQN
IILMHSERGG LPVLAFMLTA LLLYRKQYSG EQKTLEMIYK QAPRELLHLT SPLNPLPSQL
RYLQYVSRRN VGSEWPPSDK ALTLDCIILR CIPNMDGEGG CRLIFRIYGQ DPFMAADRTP
KVLFSTPKNS KFVRYYKQAD CELVKINIRC HVVGDVVLEC ISLDSNLERE LMVFRIMFNT
AFIRSNILML NRDEIDILWN TKDQFPKDFS AEVIFSDIDV APSAISIDFP GIEEKNGLSI
DDFAKVQEIF SRVDYTDVAN MLQENLETGC PKSKEIASVL HDAKVEEKSN SEAPEHVTTS
PTSDALEKQS IWSFQSSDAN STRTKFEPEE IQVVPQMATQ HTPSAVPSSD SSSTEGKTES
QELQVALQEA ELTNSSRRNV EIQEIQVSSQ QPAQSTSTFT PVLDVNSIRK KTEPQELQVA
VQRPAQPMII SQRGPQSSIS SPVSYCNSLP GSPAPISRYR SPPSALGITA LLHDHDASES
EDHSHPVASS LSSSSVSSPL SHTPKHLQLT RAIASPGQSS FVPPPPPPLP SFSGASPAYQ
PPPSLEVSPP SVKSSFQSPP HPPPPLHSFS RASPSPLVKN SLQSLPPSSS ASLAPKVENL
FRSPPPPPPL PPSSATSPSS SVKNSFSAPP PPPPPPPPLP PFSAISPSFT VKNSSSAPPP
PPPLPNVASS TTCPNSCSPQ IRTSGPPPPH APPPQSGSIS DPTSKSSVPR PPPPPPPSLA
AKGPSPNNSA HVPPVPPPPA PCAKGLSKAG DTSPQLHSVS NGNIPSIPGP PSAAPLNLKG
RGISRIGPKS LAQPRKNNLK PYHWLKLTRA MQGSLWAEAQ KPEEASKAPE IDMSELESLF
SAAAPNSDNG SRDGKSNRGA SGRKPEKVQL IELRRAYNCE IMLTKVKIPL PDLTSSVLTM
DDTALDSDQL ENLIKFCPTK EETELLKGYN GDKEKLGKCE QFFLELIKVP RVESKLRVFL
FKIQFSSQVS DLRNGLNIIN STAEEVRNSV KLKRIMQTIL YLGNALNKGT ARGSAVGFRL
DSLLKLSETR ARNNKMTLMH YLCKVLNEKS PELLEFPKDL VTLEASTKIQ LKCLAEEMQA
ISKGLEKVVQ ELTASENDGP VSETFCWTLK EFLGFAESEV RSLALLYSSV GRNADALALY
FGEDPARCPF EQVVSTLLNF VRMFVRAHEE NCKQLELEKK KAQKEADNEK LKVSTPTKKS
EHLK
//
