ID A0A1U8JY14_GOSHI Unreviewed; 771 AA.
AC A0A1U8JY14;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=ADP-ribosylation factor GTPase-activating protein AGD2-like isoform X5 {ECO:0000313|RefSeq:XP_016693184.1};
GN Name=LOC107909972 {ECO:0000313|RefSeq:XP_016693184.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016693184.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016693184.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016693184.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_016693184.1; XM_016837695.1.
DR AlphaFoldDB; A0A1U8JY14; -.
DR GeneID; 107909972; -.
DR OrthoDB; 1449795at2759; -.
DR Proteomes; UP000189702; Chromosome 20.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd08204; ArfGap; 1.
DR CDD; cd07606; BAR_SFC_plant; 1.
DR CDD; cd13250; PH_ACAP; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR045258; ACAP1/2/3-like.
DR InterPro; IPR035670; AGD1/2/3/4_BAR_plant.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR23180:SF244; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN AGD2; 1.
DR PANTHER; PTHR23180; CENTAURIN/ARF; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF01412; ArfGap; 1.
DR Pfam; PF16746; BAR_3; 1.
DR Pfam; PF00169; PH; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00105; ArfGap; 1.
DR SMART; SM00721; BAR; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 2.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS50115; ARFGAP; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}.
FT DOMAIN 296..427
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 470..626
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REPEAT 678..710
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 711..743
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 771 AA; 86991 MW; F7DCB64C7FD6F55F CRC64;
MSAFLKLEDS PMFQKQIWSL EHMADDLKNR CQILYKGSKR FMAALGEAYN GDNSFADSLE
AFGGAKDDPY SLSIGGFQGP IMSKFIKAFR ELASYKELLR SQVEHVLIDQ LMHFMNVDLQ
DAKESRRRFD KAISTYDQAR EKFVSLKKNT PGDIVAELEE DLQNSKSSFE RSRFNLVNAL
MNIEAKKKYE FLESISAIMD SHLKYFKLGF ELLKQLEPFI HQVYTYAQQA KELANAEQCS
LEKRIQEFRT QAEIDIIKTS SNIEPSTSSV GICVTGMNSD KNIEAIMQSS RNGEVQTIKQ
GYLLKRSSSL RGDWKRRFFV LDSQGTLYYY RNKGIKPTGF LHHYAGSAEY NSGVFARFRA
KYRTSSCEDN LGCRTVDLCT STIKMGAEDT DLRLCFRIIS PLKTYTLQAE NAGDRTDWVN
KITAVITSLL SSHIMQQHVE NNDYARKASS NVMLHNNLHT SEDQIGNRAE SVSAVLREIP
GNDVCAECNA HEPDWASLNL GILLCIECSG VHRNLGVHIS KVQFIHQRRE RDLMAFFLPF
SSVRSLTLDV KVWEPSIVEL FCTLGNAYCN SIWEGSLLKN ERVDESNAIN TSVTKPCPKD
AICDKEKYIN AKYVNKLLVS RDPMQLGVSQ NSINIWQAVK ADNIREVYRL ITVSDTNMND
PSACQRIKNS NDPGSCLQGC SLLHLACQRS NPVMVELLLQ FGADINMRDY HGRTPLHHCI
AIGKNPLAKH LLKRGARSSI RDGGGFSALD RAMEKGAITD EGLLILLSES D
//
