ID   A0A1U8K5C5_GOSHI        Unreviewed;      1255 AA.
AC   A0A1U8K5C5;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Paladin {ECO:0000256|ARBA:ARBA00040012};
GN   Name=LOC107912257 {ECO:0000313|RefSeq:XP_016695829.1};
OS   Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX   NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016695829.1};
RN   [1] {ECO:0000313|Proteomes:UP000189702}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX   PubMed=25893780; DOI=10.1038/nbt.3208;
RA   Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA   Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA   Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA   Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA   Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT   "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT   provides insights into genome evolution.";
RL   Nat. Biotechnol. 33:524-530(2015).
RN   [2] {ECO:0000313|RefSeq:XP_016695829.1}
RP   IDENTIFICATION.
RC   TISSUE=Leaf {ECO:0000313|RefSeq:XP_016695829.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000256|ARBA:ARBA00004514}.
CC   -!- SIMILARITY: Belongs to the paladin family.
CC       {ECO:0000256|ARBA:ARBA00037958}.
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DR   RefSeq; XP_016695829.1; XM_016840340.1.
DR   AlphaFoldDB; A0A1U8K5C5; -.
DR   STRING; 3635.A0A1U8K5C5; -.
DR   PaxDb; 3635-A0A1U8K5C5; -.
DR   GeneID; 107912257; -.
DR   KEGG; ghi:107912257; -.
DR   OrthoDB; 49159at2759; -.
DR   Proteomes; UP000189702; Chromosome 21.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IBA:GO_Central.
DR   CDD; cd14496; PTP_paladin; 2.
DR   Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 3.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   PANTHER; PTHR23339:SF96; PALADIN; 1.
DR   PANTHER; PTHR23339; TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE; 1.
DR   Pfam; PF14566; PTPlike_phytase; 3.
DR   SMART; SM01301; PTPlike_phytase; 3.
DR   SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 3.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000189702}.
FT   REGION          679..698
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1255 AA;  141240 MW;  647F66F429039211 CRC64;
     MSIPKEIEQV MKMRGGSVLG KKTILKSDHF PGCQNKRLSP LIDGAPNYRQ ADSLRVHGVA
     IPTIVGIQNV LNHIGAQKDG KQAHVLWISL REEPVVYING HPFVLRDVER PFSNLEYTGI
     NRDRVEQMEA RLKEDILMEA ARYGNKILVT DELPDGEMVD LWEQVSCNSV KTPLEVYEEL
     QLAGYLVDYE RVPITDEKSP KELDFDILVN KISQADISTE VIFNCQMGRG RTTTGMVIAT
     LVYLNRTGAS GIPRTNSIGR VFNSGSNITN NLPNSEEAIC RGEYTLIRSL IRVLEGGVEG
     KRQVDKVIDK CASMQNLREA IATYSNSILR QPDEMKREAS LSFFVEYLER YYFLICFAVY
     VHSERAALRS SSFDHTSFSD WMKARPELYS IIHRLLRRDP MGALGYASLN PSLTMVVESA
     DGRPHEVGVV AALRNGEVLG SQTVLKSDHC PGCQNASLPE RVEGAPNFRE VPGFPVYGVA
     NPTIDGIRSV IQRIGSSKGG RPVFWHNMRE EPVIYINGKP FVLREVERPY KNMLEYTGID
     RERVERMEAR LKEDILREAK RYEGAIMVIH ETDDGQIFDA WEHVNSDSVR TPLEVFKCLE
     DDGFPIKYAR VPITDGKAPK SSDFDTVAKN IASASEHTAF VFNCQMGRGR TTTGTVIACL
     VKLRIDNGRP IKVLLDEMNH EHPDGSSSSG EEIRSDATRL TSSTVKVRTK NEHGRAFGID
     DILLLWKITR LFDNGVECRE ALDAIIDRCS ALQNIRQAVL QYRKVFNQQH VEPRVRRVAL
     NRGAEYLERY FCLIAFAAYL GSEAFDGFCG QGECLMTFED WLHQRPEILA MKSSIRLRPG
     RFFTVPEELR ASLESQHGDA VMEAIVKARN GSVLGKGSIL KMYFFPGQRT STHIQIRGAP
     HVFKVDGYPV YSMATPTIIG AKEMLAYLGA KVNAGFSGQK VVVTDLREEA VVYINGTPFV
     LRELNKPVET LKHVGITGPV VEHMEARLKE DILSEVRQSG GQMLLHREEY NPSSNQSSVV
     GYWENIFADD VKTPAEVYAT LKDEGYNIVY KRIPLTRERE ALASDVDEIQ SCKDDSSGCY
     LYVSHTGFGG VAYGMAIICC RLDAEVNYGT SNVTQSLADA HLHSPPEESM SLQTSEEEAR
     RMGDYRDILS LTRVLIHGPK SKADVDIIIE RCAGAGHLRD DILHYSKELE QVPHDDDEHQ
     AYLMDMGIKA LRRYFFLITF RSYLYCTSPN ETKFTSWMVA RPELGHLCNN LRIDK
//