ID A0A1U8KBP8_GOSHI Unreviewed; 740 AA.
AC A0A1U8KBP8;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=DNA polymerase eta-like {ECO:0000313|RefSeq:XP_016699920.1};
GN Name=LOC107915273 {ECO:0000313|RefSeq:XP_016699920.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016699920.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016699920.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016699920.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_016699920.1; XM_016844431.1.
DR AlphaFoldDB; A0A1U8KBP8; -.
DR STRING; 3635.A0A1U8KBP8; -.
DR PaxDb; 3635-A0A1U8KBP8; -.
DR GeneID; 107915273; -.
DR KEGG; ghi:107915273; -.
DR OrthoDB; 118267at2759; -.
DR Proteomes; UP000189702; Chromosome 22.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005657; C:replication fork; IBA:GO_Central.
DR GO; GO:0035861; C:site of double-strand break; IBA:GO_Central.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IBA:GO_Central.
DR GO; GO:0042276; P:error-prone translesion synthesis; IBA:GO_Central.
DR GO; GO:0009314; P:response to radiation; IBA:GO_Central.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR45873; DNA POLYMERASE ETA; 1.
DR PANTHER; PTHR45873:SF1; DNA POLYMERASE ETA; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR Pfam; PF21704; POLH-Rev1_HhH; 1.
DR PIRSF; PIRSF036603; DPol_eta; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702}.
FT DOMAIN 74..314
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
FT REGION 607..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 609..626
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|RefSeq:XP_016699920.1"
SQ SEQUENCE 740 AA; 82776 MW; 4B40BF4AF0BF7502 CRC64;
NGNGVSRCTA FLQSKRCVEV GTGGHWTYSV KLPSLFFWLS LLVDKGEDYR RFGGKRGERA
LPVAKPESSD SRVIAHVDMD CFYVQVEQRK QPQLRGLPTA VVQYNEWKGG ALIAVSYEAR
KFGVKRSMRG EEAKEVCPQV QLVQVPVARG KADLSGYRNA GSEVVSILAR RGRCERASID
EVYLDLTDAA EMMLADNPPQ GMETIDEEAL KSHILGLNNE DGSDVKENVR KWIHRHNADH
RDKLLACGIL IVAELRMQVL KETEFTCSAG IAHNKMLAKL ASGMNKPAQQ TVVPFSSVKG
LLDTLPIRKM KQLGGKLGIS LQMDMGVNTV GDLLQFPEEK LQERYGINTG TWLWNIARGI
SGEEVEGRLL PKSHGSGKTF PGPRALKTVP AVQHWLNQLC EELSERLCSD LDQNKRIAHT
LTLHARAYKS SDTDSQKKFP SKSCPLRYGT AKIQEDAFNL FQAGLREYIG FYGGKTRGSH
CRGWGITSLS VSASKIVPIP SGTCSIAKYF QGQSTSHFSS MQSSDNLNTE ATLSLPSGSE
CYSEVNLSEP KIDFPKEESW IKDTVPDLDL QEQKDLSSTL SEKTQDGFIQ EDISPLLLSG
CLEQNRSKQQ QDLTKDESQF KSEYKERKGK RLEYKGTYSI IELFKSYNPN PSGSFLSHEY
NRTVGGTDAS SSSYSRDEEE GRREAWGYNI DEIDSSVMEE LPTEIQDEIK SWMQPHKRRP
NNMVKRSCTI SHYFSPSKKS
//
