ID A0A1U8KQL7_GOSHI Unreviewed; 1064 AA.
AC A0A1U8KQL7;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Protein EXPORTIN 1A-like {ECO:0000313|RefSeq:XP_016704735.1};
GN Name=LOC107919849 {ECO:0000313|RefSeq:XP_016704735.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016704735.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016704735.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016704735.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466}.
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DR RefSeq; XP_016704735.1; XM_016849246.1.
DR AlphaFoldDB; A0A1U8KQL7; -.
DR STRING; 3635.A0A1U8KQL7; -.
DR PaxDb; 3635-A0A1U8KQL7; -.
DR OrthoDB; 169519at2759; -.
DR Proteomes; UP000189702; Chromosome 4.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IBA:GO_Central.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR GO; GO:0000055; P:ribosomal large subunit export from nucleus; IBA:GO_Central.
DR GO; GO:0000056; P:ribosomal small subunit export from nucleus; IBA:GO_Central.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 3.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR041123; CRM1_repeat.
DR InterPro; IPR041235; Exp1_repeat_2.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR045065; XPO1/5.
DR InterPro; IPR014877; XPO1_C_dom.
DR InterPro; IPR040485; XPO1_repeat_3.
DR PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR PANTHER; PTHR11223:SF2; EXPORTIN-1; 1.
DR Pfam; PF08767; CRM1_C; 1.
DR Pfam; PF18777; CRM1_repeat; 1.
DR Pfam; PF18784; CRM1_repeat_2; 1.
DR Pfam; PF18787; CRM1_repeat_3; 1.
DR Pfam; PF03810; IBN_N; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SMART; SM01102; CRM1_C; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 37..103
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
SQ SEQUENCE 1064 AA; 122209 MW; C6C9AB2A870357FA CRC64;
MAAERLRDLS QPIDVSLLDA TVAAFYGTGS KQERAHADQI LRDLQNNPDM WLQVVHILQQ
TKSLNTKFFA LQVLEGVIKY RWNALPVEQR DGMKNYISEV IVQLSSNEAS FRAERLYVNK
LNIILVQILK HDWPARWRSF IPDLVAAAKT SETICENCMA ILKLETLLKF FPVPSYRNLT
LQCLTEVAAL NFGDYYNVQY VKMYNIFVVQ LQLELWFADL RILLAHCFVL YYWTILPPTT
DIPEAYAHGT SEEQAFIQNL ALFFTSFYKF HIRVLETVQE NISALLVGLE YLINISYVDD
TEVFKVCLDY WNSLVLELFD ANHNMDNPAV TANMMGLQVL SILCAAYLAT FVLATFVGKK
TSSGTSLGSE RCQLETNVPL LPGLVDGLGA QLLQRRQLYA GTMSKLRMLM ICRMAKPEEV
LIVEDENGNI VRETMKDNDV LVQYKIMRET LIYLSHLDHE DTEKQMLKKL SKQLSGEDWT
WNNLNTLCWA IGSISGSMME EQENRFLVMV IRDLLNLCEI TKGKDNKAVI ASNIMYVVGQ
YPRFLRAHWK FLKTVVNKLF EFMHETHPGV QYIFVIGNMV CKLQLKVHDM ACDTFLKIVQ
KCKRKFVIVQ VGENEPFVSE LLSALATTVA DLEPHQIHSF YESVGHMIQA ESDPHKRNEY
LQRLMELPNQ KWGEIIGQAR QSVDFLKDQD VIRTVLNILQ TNTSVASSLG THFLSQISLI
FLDMLNVYRM YSELISSSIA EGGPYASKTS YVKLLRSVKR ETLKLIETFL DKAEDQPQIG
KQFVPPMMDP VLGDYARNLP DARESEVLSL FATIINKYKV AMIDDVPRLF EAVFQCTLEM
ITKNFEDYPE HRLKFFSLLR AIATHCFAAL IRLSSQQLKL VMDSIIWAFR HTERNIAETG
LNLLLEMLKN FQASEFCNQF YRTYFLSIEQ EIFAVLTDTF HKPGFKLHVL VLQHLFCLVE
SGLLTEPLWD AATVPYPYPN NGMFVREYTI KLLSTSFPNM TAAEVSQFVN GLFDSRNDLS
TFKNHIRDFL VQSKEFSAQE QLSPLYVVCF DERIDHVILL SAGQ
//
