ID A0A1U8LIT7_GOSHI Unreviewed; 193 AA.
AC A0A1U8LIT7;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Cyclin-dependent kinase inhibitor {ECO:0000256|PIRNR:PIRNR017811};
GN Name=LOC107927899 {ECO:0000313|RefSeq:XP_016714512.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016714512.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016714512.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016714512.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleoplasm
CC {ECO:0000256|ARBA:ARBA00004642}.
CC -!- SIMILARITY: Belongs to the CDI family. ICK/KRP subfamily.
CC {ECO:0000256|ARBA:ARBA00010274, ECO:0000256|PIRNR:PIRNR017811}.
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DR RefSeq; XP_016714512.1; XM_016859023.1.
DR AlphaFoldDB; A0A1U8LIT7; -.
DR GeneID; 107927899; -.
DR OrthoDB; 1132960at2759; -.
DR Proteomes; UP000189702; Unplaced.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004861; F:cyclin-dependent protein serine/threonine kinase inhibitor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR Gene3D; 4.10.365.10; p27; 1.
DR InterPro; IPR003175; CDI_dom.
DR InterPro; IPR044898; CDI_dom_sf.
DR InterPro; IPR044275; KRP.
DR PANTHER; PTHR46776; CYCLIN-DEPENDENT KINASE INHIBITOR 4-RELATED; 1.
DR PANTHER; PTHR46776:SF7; CYCLIN-DEPENDENT KINASE INHIBITOR 6; 1.
DR Pfam; PF02234; CDI; 1.
DR PIRSF; PIRSF017811; CDK_inhib_pln; 1.
PE 3: Inferred from homology;
KW Protein kinase inhibitor {ECO:0000256|ARBA:ARBA00023013,
KW ECO:0000256|PIRNR:PIRNR017811};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702}.
FT DOMAIN 148..191
FT /note="Cyclin-dependent kinase inhibitor"
FT /evidence="ECO:0000259|Pfam:PF02234"
FT REGION 122..151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 193 AA; 21885 MW; 165034D5E2ED586B CRC64;
MGDCMRSYKR SVERAEMEAS KKRLLLSKRR KSVVSIELQE LALASPADVE LDNAITAASA
TSDVVFAGEK CCRLSSDEFS FSSCFSNGCC DVVEDSLRFV DLKAKSFETE ISTCINVNSQ
KTTPLTEEEM KSPEIKTPPS PAKQPKTPSQ EEIDEFFTVA ENYEQKRFME KYNYDIVKDM
PVDGRYQWVR LKP
//
