ID A0A1U8LIV3_GOSHI Unreviewed; 548 AA.
AC A0A1U8LIV3;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Polyphenol oxidase I, chloroplastic-like {ECO:0000313|RefSeq:XP_016714440.1};
GN Name=LOC107927826 {ECO:0000313|RefSeq:XP_016714440.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016714440.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016714440.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016714440.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
CC Evidence={ECO:0000256|ARBA:ARBA00001973};
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DR RefSeq; XP_016714440.1; XM_016858951.1.
DR AlphaFoldDB; A0A1U8LIV3; -.
DR STRING; 3635.A0A1U8LIV3; -.
DR PaxDb; 3635-A0A1U8LIV3; -.
DR GeneID; 107927826; -.
DR KEGG; ghi:107927826; -.
DR OMA; DRDESIW; -.
DR OrthoDB; 4070889at2759; -.
DR Proteomes; UP000189702; Unplaced.
DR GO; GO:0004097; F:catechol oxidase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR InterPro; IPR008922; Di-copper_centre_dom_sf.
DR InterPro; IPR022740; Polyphenol_oxidase_C.
DR InterPro; IPR022739; Polyphenol_oxidase_cen.
DR InterPro; IPR002227; Tyrosinase_Cu-bd.
DR PANTHER; PTHR11474:SF76; TYROSINASE; 1.
DR PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR Pfam; PF12142; PPO1_DWL; 1.
DR Pfam; PF12143; PPO1_KFDV; 1.
DR Pfam; PF00264; Tyrosinase; 1.
DR PRINTS; PR00092; TYROSINASE.
DR SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR PROSITE; PS00498; TYROSINASE_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Signal {ECO:0000256|SAM:SignalP};
KW Thioether bond {ECO:0000256|ARBA:ARBA00022784}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..548
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010565748"
FT DOMAIN 318..329
FT /note="Tyrosinase copper-binding"
FT /evidence="ECO:0000259|PROSITE:PS00498"
SQ SEQUENCE 548 AA; 63265 MW; BC15B3F2DAC81B70 CRC64;
MAEKKWILIL SLTFIIAVSQ VHHLYMGELT SIMLEKLQQW RKPFNNGGKN LAIGPNLTAC
HSSYGRPDLL VYCCPPGFQN PVPFTDFKFP DPSPVRVRRP AHLFNESFIA KYNKALSIMK
SLPYDDPRSF HRQANLHCQF CTGAYEMLNS SGSELNIHRT WMFFPWHRMM IYFHERILGS
LIGDDTFALP FWAWDIPDGM TIPDFYVDKS SPFFHSQRDF SHFPPRVADL DYSPDDNDPR
FDRKEQTETN LAFMYNRMVS GAKKTELFMG CTYKAGEKNC DSPGTIESAP HNTLHTWIGS
GLNPGREDMG KFYSAAKDPV FYAHHSNIDR LWEVWRDIND RKLDIDDSDW LNSFFLFYDE
NLNLVKIKVK DVLDITKLGY SYEEVHRPWL NHRPPPSVPP EQARRITNLK QNENPVFSSD
FRRVLDGKLT VTVNRSVKRE KVDEEETVVV YGIVVRGNEY VKFDVYVNLS DDTKMNPKFR
EFAGTFAYIP GGGRGGPNLK KMKLKLGISE LLKDLKADED ESIWVTLVPR TTSCSNVSIE
GIKIEYVK
//
