ID A0A1U8LN67_GOSHI Unreviewed; 655 AA.
AC A0A1U8LN67;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=ABC transporter G family member 22-like isoform X2 {ECO:0000313|RefSeq:XP_016714903.1};
GN Name=LOC107928227 {ECO:0000313|RefSeq:XP_016714903.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016714903.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016714903.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016714903.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_016714903.1; XM_016859414.1.
DR AlphaFoldDB; A0A1U8LN67; -.
DR OrthoDB; 936137at2759; -.
DR Proteomes; UP000189702; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR48041:SF94; ABC TRANSPORTER G FAMILY MEMBER 22; 1.
DR PANTHER; PTHR48041; ABC TRANSPORTER G FAMILY MEMBER 28; 1.
DR Pfam; PF01061; ABC2_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 420..440
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 452..475
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 496..522
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 528..550
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 562..581
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 154..395
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 655 AA; 72933 MW; BD194A1D4ABA96ED CRC64;
MEKGSHSSST TLARTKSDQL VETLAAAFKS PRQSDQQTPP GTSESGGTLS RKSSKRVMMG
ASPRRSSGEN NNTYIRKSRS AQMKLDLEEL SSGAALSRAS SASLGLSFSF TGFTVPPDEI
ADSKPFSDDD IPEDVEARTS KMKFQTEPTL PIYLKFTDVT YKVIIKGMTS CEERDILNGI
TGAVNPGEVL ALMGPSGSGK TTLLNLLGGR LIQSTVSGSI TYNDQPYSKF LKSRIGFVTQ
DDVLFPHLTV KETLTYAARL RLPKVLTRQQ KEKRAVDVIY ELGLERCQDT MIGGSFVRGV
SGGERKRVCI EFLLDLANGN LTDISVPSEL EDKVQMENSE TETGNGKPPP AVVHEYLVEA
YESRVADTEK KKLMAPLPLD EELKSKVSSS KRQWGASWWQ QYCILFCRGI KERKHDYFSW
LRITQVLSTA IILGLLWWQS DSKTIRGRQD QAGLLFFIAV FWGFFPVFTA IFTFPQERAM
LGKERAADMY RLSAYFLART TSDLPLDLIL PVLFLLVVYF MAGLKLSASH FFLSMLTVFL
CIVAAQGLGL AIGATLMDLK RATTLASVTV MTFMLAGGYF VKKVPVFISW IRYMSFNYHT
YKLLLKVQYQ DIMPTVNGIK TDSGLKEVGA LVAMIFGYRF LAYLSLRKMQ LHCEA
//
