ID A0A1U8LPA1_GOSHI Unreviewed; 560 AA.
AC A0A1U8LPA1;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=U4/U6 small nuclear ribonucleoprotein PRP4-like protein {ECO:0000313|RefSeq:XP_016716387.1};
GN Name=LOC107929465 {ECO:0000313|RefSeq:XP_016716387.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016716387.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016716387.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016716387.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_016716387.1; XM_016860898.1.
DR AlphaFoldDB; A0A1U8LPA1; -.
DR STRING; 3635.A0A1U8LPA1; -.
DR PaxDb; 3635-A0A1U8LPA1; -.
DR OrthoDB; 5476798at2759; -.
DR Proteomes; UP000189702; Chromosome 4.
DR GO; GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IBA:GO_Central.
DR GO; GO:0030621; F:U4 snRNA binding; IBA:GO_Central.
DR GO; GO:0017070; F:U6 snRNA binding; IBA:GO_Central.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 4.10.280.110; Pre-mRNA processing factor 4 domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR014906; PRP4-like.
DR InterPro; IPR036285; PRP4-like_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19846:SF0; SFM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR19846; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF08799; PRP4; 1.
DR Pfam; PF00400; WD40; 7.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00500; SFM; 1.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF158230; PRP4-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 3.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 6.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ribonucleoprotein {ECO:0000313|RefSeq:XP_016716387.1};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 128..181
FT /note="Pre-mRNA processing factor 4 (PRP4)-like"
FT /evidence="ECO:0000259|SMART:SM00500"
FT REPEAT 303..335
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 344..385
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 386..427
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 428..469
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 470..512
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 513..544
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 65..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..50
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 77..93
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 560 AA; 61824 MW; E08E9549F0535665 CRC64;
MEVDDDNSPS TSAAVPDGET PVPTANSTPV QPPAVPPAVV PPTIAPLPAV VPPIAPIPAV
RPPVFKPPVP QNGEVKAVDS DSDHEDDGRA TAGEYEISEE SRLVRERQEK AMQELLMKRR
AAALAVPTND MAVRTRLRRL GEPITLFGER EMERRERLRM IMAKLDSEGQ LEKLMKAHEE
EEAAISAKAE DIEEDIEYPF YTEGPKELLD ARIDIAKYSI VKAAARLQRA RRKRDDPDED
MDAEIDWALR QAGNLVLDCS EIGDDRPLSG CSFSRDGKLL ATCSLSGVAK LWSMPRVSKV
SALKGHTERA TDVTFSPVHD LLATASADRT AKLWSSDGSL LKTFGGHLDR LARIAFHPSG
KYLGTTSFDK TWRLWDIDTG MELLLQEGHS RSVYGIAFHQ DGSLVASCGL DALARVWDLR
TGRSILAFEG HVKPVLCASF SPNGYHLATG GEDNTCRIWD LRKKKSLYII PAHSNLISQV
KFEPQEGYYL VTSSYDMTAK VWSGRDFKPV KSLPGHEAKV TASDISADGR YIVTVSHDRT
IKLWTAGNIE QENDMDWTEG
//
