ID   A0A1U8LRW2_GOSHI        Unreviewed;       868 AA.
AC   A0A1U8LRW2;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=Importin subunit beta-1-like {ECO:0000313|RefSeq:XP_016717317.1};
GN   Name=LOC107930238 {ECO:0000313|RefSeq:XP_016717317.1};
OS   Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX   NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016717317.1};
RN   [1] {ECO:0000313|Proteomes:UP000189702}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX   PubMed=25893780; DOI=10.1038/nbt.3208;
RA   Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA   Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA   Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA   Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA   Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT   "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT   provides insights into genome evolution.";
RL   Nat. Biotechnol. 33:524-530(2015).
RN   [2] {ECO:0000313|RefSeq:XP_016717317.1}
RP   IDENTIFICATION.
RC   TISSUE=Leaf {ECO:0000313|RefSeq:XP_016717317.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the importin beta family. Importin beta-1
CC       subfamily. {ECO:0000256|ARBA:ARBA00010907}.
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DR   RefSeq; XP_016717317.1; XM_016861828.1.
DR   AlphaFoldDB; A0A1U8LRW2; -.
DR   STRING; 3635.A0A1U8LRW2; -.
DR   PaxDb; 3635-A0A1U8LRW2; -.
DR   GeneID; 107930238; -.
DR   KEGG; ghi:107930238; -.
DR   OMA; EMTEYIN; -.
DR   OrthoDB; 124901at2759; -.
DR   Proteomes; UP000189702; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0061608; F:nuclear import signal receptor activity; IBA:GO_Central.
DR   GO; GO:0008139; F:nuclear localization sequence binding; IBA:GO_Central.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR040122; Importin_beta.
DR   PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR   PANTHER; PTHR10527:SF1; IMPORTIN SUBUNIT BETA-1; 1.
DR   Pfam; PF13513; HEAT_EZ; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000189702}.
FT   DOMAIN          21..101
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
SQ   SEQUENCE   868 AA;  95784 MW;  798E43688305CB52 CRC64;
     MEVTQVLLNA QSIDGAVRKN AEESLKHFQE QNLTGFLLLL SGELVSEEKP VETRKLAGLI
     LKNALDAKDQ QRKVELVQRW LSLDGNAKSQ IKAGLLKTLS SPVSDARSTA SQVIAKVAGI
     ELPHKQWPEL VGSLLSNVHQ LPAHAKQATL ETLGYLCEEV SPDVIDQDQV NKILTAVVQG
     MSASEGNTDV RLAATRALYN ALGFAQANFS NDMERDYLMR VVCEATLSPE VRIRQAAFEC
     LVSISSTYYE KLAPYIQDIF NITAKAVRED EEPVALQAIE FWSSICDEEI DILEEYGGDF
     TGDSDIPCFY FIKQAIPALV PMLLETLLKQ EEDQDQDEGA WNIAMAGGTC LGLVARTVGD
     DIVPLVVPFI EENITKQDWR QREAATYAFG SILEGPSPAK LIPLVNVALN FMLSALTKDP
     NSHVKDTTAW TLGRIFEFLH GSAVDSPIIT QANCQQIVVV LLQSMKDTPN VAEKACGALY
     FLAQGYEEVG PSSPLTPFFQ EIVQSLLTVT HREDARESRL RTAAYETLNE VVRCSTDETA
     PLVLQLVPVI IMELHNTVEG QKLSSDEREK QSELQGLLCG CLQVIIQKLG SSESTKYLFL
     QYADQIMGLF LSVFACRSAT VHEEAMLAIG ALAYATGPDF VKYMPEFYRY LEMGLQNFEE
     YQVCAVTVGV VGDICRALEE KVVPYCDGIM TQLLKNLSSN QLHRSVKPPI FSCFGDIALA
     VGEYFEKYLM WAMSALQSAA ELSTHTTGDD ELIEYINTLR NGILEAYSGI FQGFKNSPKT
     QLLIPYAPHI LQFLDGIYME KDMDDVVMKT AIGVLGDLAD TLGSHAASLI QQSVSSKDFL
     NECLSSEDVM IKESAEWAKL AISRAISV
//