ID A0A1U8LSZ2_GOSHI Unreviewed; 776 AA.
AC A0A1U8LSZ2;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Subtilisin-like protease SBT3.8 {ECO:0000313|RefSeq:XP_016716533.1};
GN Name=LOC107929577 {ECO:0000313|RefSeq:XP_016716533.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016716533.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016716533.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016716533.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR RefSeq; XP_016716533.1; XM_016861044.1.
DR AlphaFoldDB; A0A1U8LSZ2; -.
DR STRING; 3635.A0A1U8LSZ2; -.
DR PaxDb; 3635-A0A1U8LSZ2; -.
DR GeneID; 107929577; -.
DR KEGG; ghi:107929577; -.
DR OrthoDB; 11910at2759; -.
DR Proteomes; UP000189702; Unplaced.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02120; PA_subtilisin_like; 1.
DR CDD; cd04852; Peptidases_S8_3; 1.
DR Gene3D; 2.60.40.2310; -; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.70.80; Peptidase S8 propeptide/proteinase inhibitor I9; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034197; Peptidases_S8_3.
DR InterPro; IPR010259; S8pro/Inhibitor_I9.
DR InterPro; IPR037045; S8pro/Inhibitor_I9_sf.
DR InterPro; IPR045051; SBT.
DR InterPro; IPR041469; Subtilisin-like_FN3.
DR PANTHER; PTHR10795; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN; 1.
DR PANTHER; PTHR10795:SF848; SUBTILISIN-LIKE PROTEASE; 1.
DR Pfam; PF17766; fn3_6; 1.
DR Pfam; PF05922; Inhibitor_I9; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..776
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010545748"
FT DOMAIN 34..112
FT /note="Inhibitor I9"
FT /evidence="ECO:0000259|Pfam:PF05922"
FT DOMAIN 138..590
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 669..764
FT /note="Subtilisin-like protease fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF17766"
FT ACT_SITE 147
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 224
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 554
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 776 AA; 82534 MW; 29634B9812F88113 CRC64;
MGSNPLPSFV IVLILLVLNG QGPMTAKVEA KSTVHIVYLG ERQHDDPKRA TDSHHDLLAT
VVGSKEIASD LMVYSYRHGF SGFAAKLTES QAQKLSELPG VVRVIPNTLH RLQTTRSWDF
LGLSSHYPNH VLQNSKMGDG VIIGVFDTGI WPESKAFSDE GLGPIPSHWK GVCKSGDQFN
AATHCNRKII GARWFIDGFL AEYGRLLNTS DDPEFLSPRD ANGHGTHTSS TASGAYVRNV
SYRGLLSGTV RGGAPRARLA IYKVCWNVLG GQCASADILK AFDEAIHDGV DVLSLSIGYS
LPLFSDVDER DGIATGSFHA VARGITVVCG AANEGPSAQT VQNTAPWILT VAASTMDRAL
PTPIMLGNNK TFLGQAIFTG KEKGFTSLTY PEGTGLDPTS AGACQSLSLN STLVAGKVVL
CFASVTGRVA IRLAAATVQE AGGIGLIIAK NPRDALIECR DGFPCIEVDY EIGTRILYYI
LSTKSPTVKL GHSKTLVGKP VSAKVAFFSS RGPSSIAPEI LKPDITAPGV NILAATSQLD
QWMDGGYAIH SGTSMATPHV SGIVALLKAI HPDWSPAAIK SALVTTARTK DASGFPLFAE
GSPKKLANPV DCGGGIVNPN GAADPGLVYD MGLSDYIHYL CAMGYNNSAI SRLTGQSTAC
SAEKPSFLDV NLPSITISSL RNSVTLTRTV TNVGSPNSIY RADIETPTGM TVTVKPHILV
FNSRTKKISF NVTICATKQV NTGYFFGSLT WRNEQNAVRI PLSVKTEILQ SYADDN
//
