ID A0A1U8LTB1_GOSHI Unreviewed; 835 AA.
AC A0A1U8LTB1;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Calcium-binding mitochondrial carrier protein SCaMC-1-like {ECO:0000313|RefSeq:XP_016717822.1};
GN Name=LOC107930647 {ECO:0000313|RefSeq:XP_016717822.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016717822.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016717822.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016717822.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004448}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_016717822.1; XM_016862333.1.
DR AlphaFoldDB; A0A1U8LTB1; -.
DR STRING; 3635.A0A1U8LTB1; -.
DR PaxDb; 3635-A0A1U8LTB1; -.
DR GeneID; 107930647; -.
DR KEGG; ghi:107930647; -.
DR OrthoDB; 1207074at2759; -.
DR Proteomes; UP000189702; Unplaced.
DR GO; GO:0005743; C:mitochondrial inner membrane; IBA:GO_Central.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0000095; F:S-adenosyl-L-methionine transmembrane transporter activity; IBA:GO_Central.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR002067; Mit_carrier.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR PANTHER; PTHR45667:SF19; MITOCHONDRIAL SUBSTRATE CARRIER FAMILY PROTEIN; 1.
DR PANTHER; PTHR45667; S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN; 1.
DR Pfam; PF00153; Mito_carr; 3.
DR PRINTS; PR00926; MITOCARRIER.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 387..422
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REPEAT 553..633
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 642..724
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 733..818
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REGION 175..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 307..330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 835 AA; 91678 MW; B6328F44DA58A297 CRC64;
MLSKNDPIES ISSSIQFVKE AFLPLELGIK KAAKDVESCF GVSNDKGKHV ELIPQLNVSD
RNDKVQIFGM KKSDGNFGSI LNNGQCCVGS EEGKKGPSVK VPIKAFIGMF SPGNGKNNEK
VEAVRKGLNE KDVDRDEGSC MNCFQFSATW SVLVNGFVQA MPSSFNTGRK RIQKMGDKDK
GCRHSSTHDM KSKASSECKH REAKAQFSAK NEGLEHSDGK HVECFIGLIL DQLTQNLQKF
DQLLQESNRK HCECPQTPSP PSQFDYFKVV ASIWEGQKAD VNGFLGNLKF ARVGGVPSGM
VGVASHVNEE GDDDVSTGRR EESAGNSPQK LASGILSIPL SNVGRLRSTL STVSLTELVE
LLPLLGRSSQ DHPDKKKLFS VQDFFRYTES EGRRFFEELD RDGDGQVTLE DLEVAMRKRK
LPQRYAREFM RRTRSHLFSK SFNWKQFLSL MEQKEPTILR AYTSLCLSKS GTLQKSEILA
SLKNAGLPAN EDNAVAMMRF LNADTEESIS YGHFRNFMLL LPSDRLLQDD PRNIWFEAAT
VVAVAPPVEI HAGSVLKSAL AGGLSCALST SLLHPVDTIK TRVQASTLTF PEIISKLPQI
GVRGLYRGSI PAILGQFSSH GLRTGIFEAS KLVLINVAPN LPDIQVQSMA SFCSTLLGTA
VRIPCEVLKQ RLQAGLFDNV GEAIVGTWNQ DGLKGFFRGT GATLCREVPF YVAGMGLYAE
SKKLAQQLLQ RELEPWETIA VGAVSGGLAA VVTTPFDVMK TRMMTAPGGR PISMSVVAFS
ILRHEGPLGL FKGAVPRFFW IAPLGAMNFA GYELAKKAMV KNEEDQLSQK KLAKI
//
