ID A0A1U8M8H8_GOSHI Unreviewed; 332 AA.
AC A0A1U8M8H8;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Bifunctional nuclease 1-like {ECO:0000313|RefSeq:XP_016723141.1, ECO:0000313|RefSeq:XP_016723142.1};
GN Name=LOC107935093 {ECO:0000313|RefSeq:XP_016723141.1,
GN ECO:0000313|RefSeq:XP_016723142.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016723141.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016723141.1, ECO:0000313|RefSeq:XP_016723142.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016723141.1,
RC ECO:0000313|RefSeq:XP_016723142.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Bifunctional nuclease with both RNase and DNase activities.
CC Involved in basal defense response. Participates in abscisic acid-
CC derived callose deposition following infection by a necrotrophic
CC pathogen. {ECO:0000256|ARBA:ARBA00025428}.
CC -!- SIMILARITY: Belongs to the bifunctional nuclease family.
CC {ECO:0000256|ARBA:ARBA00009095}.
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DR RefSeq; XP_016723141.1; XM_016867652.1.
DR RefSeq; XP_016723142.1; XM_016867653.1.
DR STRING; 3635.A0A1U8M8H8; -.
DR PaxDb; 3635-A0A1U8M8H8; -.
DR GeneID; 107935093; -.
DR KEGG; ghi:107935093; -.
DR OMA; CHINTRR; -.
DR OrthoDB; 304718at2759; -.
DR Proteomes; UP000189702; Unplaced.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0030891; C:VCB complex; IBA:GO_Central.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR Gene3D; 3.10.690.10; Bifunctional nuclease domain; 1.
DR InterPro; IPR036104; BFN_sf.
DR InterPro; IPR003729; Bi_nuclease_dom.
DR PANTHER; PTHR15160:SF3; BIFUNCTIONAL NUCLEASE 1; 1.
DR PANTHER; PTHR15160; VON HIPPEL-LINDAU PROTEIN; 1.
DR Pfam; PF02577; BFN_dom; 1.
DR SUPFAM; SSF103256; Hypothetical protein TM0160; 1.
DR PROSITE; PS51658; BFN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000189702}.
FT DOMAIN 124..259
FT /note="BFN"
FT /evidence="ECO:0000259|PROSITE:PS51658"
SQ SEQUENCE 332 AA; 37060 MW; B116D134B2445E04 CRC64;
MVCLQGPVIC PAVDSKQVGV YTLPFNGPFP RSRLHQSDIW GYRGIVDGKG KPRGISGHLK
RRRRFNTTVQ CMFSSSSDGN GSMAENFNEN NEDYVNSSVV EAVEVRSGAD GFMIKMRDGK
HLRCVHNNPQ GGHLPDYAPH PAIVLKMEDG TGLLLPIIVL EMPSALLMAA LRNVQIARPT
MYQVVKNMID KMGYTVKLVR VTKRVHEAYF AQLYLTKVGD ETESVCFDLR PSDAINIAVR
CKVPIQVNKY LAYSDGMCVI EPGKLSTQSP ASDGLLFTEL DQPSGQHCLD TEEFNIVCDL
NKAINQERYK DAADLRDKLG QFRAQRNLKK YT
//
