ID A0A1U8MDA8_GOSHI Unreviewed; 829 AA.
AC A0A1U8MDA8;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=beta-galactosidase {ECO:0000256|ARBA:ARBA00012756};
DE EC=3.2.1.23 {ECO:0000256|ARBA:ARBA00012756};
GN Name=LOC107935429 {ECO:0000313|RefSeq:XP_016723559.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016723559.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016723559.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016723559.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC in beta-D-galactosides.; EC=3.2.1.23;
CC Evidence={ECO:0000256|ARBA:ARBA00001412};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC {ECO:0000256|ARBA:ARBA00009809, ECO:0000256|RuleBase:RU003679}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_016723559.1; XM_016868070.1.
DR AlphaFoldDB; A0A1U8MDA8; -.
DR PaxDb; 3635-A0A1U8MDA8; -.
DR GeneID; 107935429; -.
DR KEGG; ghi:107935429; -.
DR OrthoDB; 5489808at2759; -.
DR Proteomes; UP000189702; Chromosome 1.
DR GO; GO:0005773; C:vacuole; IBA:GO_Central.
DR GO; GO:0004565; F:beta-galactosidase activity; IBA:GO_Central.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd22842; Gal_Rha_Lectin_BGal; 1.
DR Gene3D; 2.60.120.740; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR048913; BetaGal_gal-bd.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR041392; GHD.
DR InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR InterPro; IPR001944; Glycoside_Hdrlase_35.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR000922; Lectin_gal-bd_dom.
DR InterPro; IPR043159; Lectin_gal-bd_sf.
DR PANTHER; PTHR23421:SF174; BETA-GALACTOSIDASE 7; 1.
DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR Pfam; PF21467; BetaGal_gal-bd; 1.
DR Pfam; PF02140; Gal_Lectin; 1.
DR Pfam; PF17834; GHD; 1.
DR Pfam; PF01301; Glyco_hydro_35; 1.
DR PRINTS; PR00742; GLHYDRLASE35.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 2.
DR PROSITE; PS50228; SUEL_LECTIN; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..829
FT /note="beta-galactosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010522475"
FT DOMAIN 741..825
FT /note="SUEL-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50228"
SQ SEQUENCE 829 AA; 93382 MW; 96F1F507A475E1DD CRC64;
MNIFNLLFTA FIFSFILFHS TALTVTHDSR SIIIDGNHRI ILSGSIHYPR STAQMWPDLI
RKAKEGGLDA VETYVFWNAH EPARRLYDFS GNLDLIRFLK TIQDQGLYAI LRIGPYTCAE
WNYGGFPVWL HNMPGVSLRT KNDVFMNEME NCTTWIVDMV KKEKLFASQG GNIILAQVEN
EYGNVMEPYG DEGKSYINWC AQMADSLDIG VPWIMCQQAA PPKPMLETCN GWYCDEYKPK
DPNTPKLWTE NWTGWFKSWG GADPFRTAED LAYSVARFFQ KGGTLQNYYM YHGGTNFGRT
SGGPYITTTY DYNAPLDEYG NLNQPKWGHL KQLHDVLHSI EYILTNGNVK NEKLSNLVMA
SIYQTKEKSS CFLSKTNTKI DANVNFGGIN YFVPAWSISI LPDCREEAYN TAKVSSQTSL
MVKKLNKAED EPSSLKWMWR PELIESTSVQ GRGDVSVNKI VDQKDMANDA SDYLWYMTSI
DVAKDDPMLN GTVTLCVNDT GHVLHAFFNG EYIGSQWSKY GNNNVTYVFE RNIKPSPGKN
LISLLSVTVG LKNYGPMFDL VGAGITSPIE LVLNKNDVKD LSSNKWTYKV GLNGISNKFF
DTDCASKSSS KWVSDPISVD RNFTWYKTTF KAPLGNKPVV VDLLGLGKGM AWVNGHSLGR
YWPSYIADKQ LCKTETCDYR GRYSDSKCVS KCGEPTQRWY HVPRSFLKDG ENTLVLFEEF
GGNPSGIQFQ TVEIGSVCIN THEGKEVELS CQDRPISKIK FASFGSPQGV CGSFDKSESD
SEVDALSILE KECLGKESCS FKITEDKFGR PSCEVKKLAV EAVCEDFTF
//
