ID A0A1U8MJL3_GOSHI Unreviewed; 325 AA.
AC A0A1U8MJL3;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Transmembrane protein 45A {ECO:0000313|RefSeq:XP_016726975.1};
GN Name=LOC107938360 {ECO:0000313|RefSeq:XP_016726975.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016726975.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016726975.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016726975.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TMEM45 family.
CC {ECO:0000256|ARBA:ARBA00006948}.
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DR RefSeq; XP_016726975.1; XM_016871486.1.
DR AlphaFoldDB; A0A1U8MJL3; -.
DR PaxDb; 3635-A0A1U8MJL3; -.
DR GeneID; 107938360; -.
DR KEGG; ghi:107938360; -.
DR OrthoDB; 1275684at2759; -.
DR Proteomes; UP000189702; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR006904; DUF716.
DR PANTHER; PTHR46285:SF3; PROTEINASE INHIBITOR I4, SERPIN (DUF716); 1.
DR PANTHER; PTHR46285; PROTEINASE INHIBITOR I4, SERPIN (DUF716)-RELATED; 1.
DR Pfam; PF04819; DUF716; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Transmembrane {ECO:0000256|SAM:Phobius, ECO:0000313|RefSeq:XP_016726975.1};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 47..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 155..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 281..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 325 AA; 36815 MW; 3BB32BF0338C7609 CRC64;
MGTLVGHVAP GFAFFALGFW HLFNHIKLHS LNPNSYTSFP WFPTLKFRYL ELVLIMVGSS
ISISMELFIG PAKHQPFDTD GTIPSNHLHN FEHSAISMTF FIYAAFSIVL DKTSINIDLM
FKHSLTQFLG AIAFAQQLFL FHLHSADHMG VEGQYHLLLQ SAIVVSLVTT LMGIGYPKSF
MVSFIRSLSI LYQGLWLMTM GFMLWTPNLI PKGCFIHLEV GHQVVKCSSD EALHRAKSLV
NIEFSWALIG VTIFAMTFYL VLVKLYGQKV EYSTLKSHEN DRFELGEEEE EEEDVESQKG
SNKQGEPTKG FIHMGKGYAI MDIER
//
