ID A0A1U8N453_GOSHI Unreviewed; 657 AA.
AC A0A1U8N453;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Heat shock protein 83-like {ECO:0000313|RefSeq:XP_016733867.1};
GN Name=LOC107944565 {ECO:0000313|RefSeq:XP_016733867.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016733867.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016733867.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016733867.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the heat shock protein 90 family.
CC {ECO:0000256|ARBA:ARBA00008239}.
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DR RefSeq; XP_016733867.1; XM_016878378.1.
DR AlphaFoldDB; A0A1U8N453; -.
DR STRING; 3635.A0A1U8N453; -.
DR PaxDb; 3635-A0A1U8N453; -.
DR GeneID; 107944565; -.
DR KEGG; ghi:107944565; -.
DR OrthoDB; 547579at2759; -.
DR Proteomes; UP000189702; Unplaced.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0032991; C:protein-containing complex; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR GO; GO:0034605; P:cellular response to heat; IBA:GO_Central.
DR GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR GO; GO:0050821; P:protein stabilization; IBA:GO_Central.
DR CDD; cd16927; HATPase_Hsp90-like; 1.
DR Gene3D; 3.30.230.80; -; 1.
DR Gene3D; 3.40.50.11260; -; 1.
DR Gene3D; 1.20.120.790; Heat shock protein 90, C-terminal domain; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR HAMAP; MF_00505; HSP90; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR019805; Heat_shock_protein_90_CS.
DR InterPro; IPR037196; HSP90_C.
DR InterPro; IPR001404; Hsp90_fam.
DR InterPro; IPR020575; Hsp90_N.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR PANTHER; PTHR11528; HEAT SHOCK PROTEIN 90 FAMILY MEMBER; 1.
DR PANTHER; PTHR11528:SF124; HEAT SHOCK PROTEIN 90-1-LIKE; 1.
DR Pfam; PF13589; HATPase_c_3; 1.
DR Pfam; PF00183; HSP90; 1.
DR PIRSF; PIRSF002583; Hsp90; 1.
DR PRINTS; PR00775; HEATSHOCK90.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF110942; HSP90 C-terminal domain; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS00298; HSP90; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Stress response {ECO:0000313|RefSeq:XP_016733867.1}.
FT DOMAIN 33..188
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|SMART:SM00387"
FT REGION 224..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 224..243
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 657
FT /evidence="ECO:0000313|RefSeq:XP_016733867.1"
SQ SEQUENCE 657 AA; 75732 MW; 7B9F6055501EBAC2 CRC64;
MADVHMGSES ETFAFQAEIN QLLSLIINTF YSNKEIFLRE LISNASDALD KIRFEGLTDK
SKLDAQPELF IRIIPDKANK TLSIVDSGVG MTKADLVNNL GTIARSGTKE FMEALQAGAD
VSMIGQFGVG FYSAYLVAEK VIVTTKHNDD EQYIWESQAG GSFTVTRDLG GEPLGRGTKI
TLFLKEDQLE YLEERRIKDL VKKHSDFISY PIYLWTEKTI EKEVSDDEDE ETKKEEEGDV
EEVDEDKEKK SKKKKVKEVS HEWQLINKQK PIWLRKPEEI TKEEYASFYK SITNDWEDHL
AVKHFSVEGQ LEFKAILFVP RRAPFDLFDT RKKLNNIKLY VRRVFIMDNC EELIPEYLSF
VKGVVDSDDL PLNISREMLQ QNKILKVIRK NLVKKCIEMF FEIAENKDDY KKFYDAFSKN
IKLGIHEDSQ NRAKLADLLR YYSTKSGDEI TSLKDYVTRM KEGQKDIYYI TGESKKAVEN
SPFLERLKKK GYEVLFMVDA IDEYAVGQLK EYDGKKLVSA TKEGLKLDEE SEDEKKKREE
KKKSFENLCK TIKEILGDKV EKVVVSDRIV DSPCCLVTGE YGWTANMERI MKAQALRDNS
MSAYMSSKKT MEINPDNGIM EELRKRAEVD KNDKSVKDLV LLLYETALLT SGFSLDD
//
