ID A0A1U8NA38_GOSHI Unreviewed; 1028 AA.
AC A0A1U8NA38;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Epidermal growth factor receptor substrate 15-like {ECO:0000313|RefSeq:XP_016734659.1};
GN Name=LOC107945243 {ECO:0000313|RefSeq:XP_016734659.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016734659.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016734659.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016734659.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_016734659.1; XM_016879170.1.
DR AlphaFoldDB; A0A1U8NA38; -.
DR STRING; 3635.A0A1U8NA38; -.
DR PaxDb; 3635-A0A1U8NA38; -.
DR GeneID; 107945243; -.
DR KEGG; ghi:107945243; -.
DR OrthoDB; 457655at2759; -.
DR Proteomes; UP000189702; Chromosome 5.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IBA:GO_Central.
DR GO; GO:0016197; P:endosomal transport; IBA:GO_Central.
DR CDD; cd00052; EH; 2.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR000261; EH_dom.
DR PANTHER; PTHR11216:SF137; CALCIUM-BINDING EF HAND FAMILY PROTEIN; 1.
DR PANTHER; PTHR11216; EH DOMAIN; 1.
DR Pfam; PF12763; EF-hand_4; 1.
DR Pfam; PF13202; EF-hand_5; 1.
DR SMART; SM00054; EFh; 4.
DR SMART; SM00027; EH; 2.
DR SUPFAM; SSF47473; EF-hand; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 3.
DR PROSITE; PS50031; EH; 2.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Receptor {ECO:0000313|RefSeq:XP_016734659.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702}.
FT DOMAIN 4..39
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 5..94
FT /note="EH"
FT /evidence="ECO:0000259|PROSITE:PS50031"
FT DOMAIN 40..73
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 375..410
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 376..455
FT /note="EH"
FT /evidence="ECO:0000259|PROSITE:PS50031"
FT REGION 162..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 279..307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 321..375
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 498..555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 730..760
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 777..837
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 864..913
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 966..985
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 996..1028
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 598..632
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 178..215
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..249
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 321..372
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..546
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 744..760
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 778..793
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 868..882
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 890..913
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1006..1028
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1028 AA; 111357 MW; D7CB1241EC67D235 CRC64;
MAGQTQDQFE VYFKKADLDG DGRISGVEAV SFFQGAGLSK QVLAQIWAYA DQSHSGFLSK
QEFFNALKLV TVAQRRELTP DIVKAALYGP AAAKIPAPQI NFPATTQMGG AVPPSSPSVG
FRGPGVPNAG MSQQHFPSQQ NLSMRPQQTM PAATALHPSQ GIAAPEFSRG GNIVGQPQAM
PAGSTPLSHQ SMPTVATGPS LTNQNMSSNW LSGRPGGAST GPRGVAPSTA PRPQAAVSMS
SQPTANDSKA LAVSGNGLAS GSAFGSDAFS ATSFTPKQEL STQTFSPHSA PASPGITPVS
SGAQPLVKSN SLDSLQSTFS MHSAGSQSQR PYSSPIQGQP VSSPSSSFTP SGISAGNVNA
APNSSQPPWP KMKQSDVQKY TKVFMEVDTD RDGKITGEQA RNLFLSWRLP REVLKQVWDL
SDQDSDSMLS LREFCFALYL MERYREGRPL PPALPRDVLF DETLLSMTGQ PNVSYGNAAW
GPNPGFGHQS GMAAQTITPS AGVKPPVRPN ASADTTTMSN QQKPREPVLD DSFGTQPNNN
GQNLENGAAG DVMADGKKVD GTEKVILDSR EKLEFYREKM QELVLYKSRC DNRLNEITER
AIADKREAEM LAKKYEEKYK QVAEIASKLT VEEAKFREIQ GRKTELHHAI VNMEQGGSAD
GILQVRADRI QSDLEELMKA LTERCKKHGY DVKSAAVIEL PTGWQPGVPD GAALWDEEWD
KFEDEGFGNE LTIDVEKGTV SQRGKASPDG SLTPDSTSYA DEKTANLFSA GERAIESESV
YTHSEDESAR SPRGSPTDRN SVESPSKPFS DDPFGKSTEA EAERQQNFDE SGWGTFDNDD
MDSVWGFNSL NTKDSDKARD FFGSSDFDVH TRTESPNAES FYDKKSPFTF EDSVPSTPLS
KFGNSPSRFS EASRDQFDSF SRFDSFSMHD GGFSQQPDRL TRFDSINSSK DFGSGFSRFD
SINNSKDFGS GFSPQPETLT RFDSISSSKD FGHGFSFDDS DPFGSSGPFK VSSDQQSPKK
SSDNWRAF
//
