ID A0A1U8NAF8_GOSHI Unreviewed; 1012 AA.
AC A0A1U8NAF8;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN Name=LOC107945328 {ECO:0000313|RefSeq:XP_016734779.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016734779.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016734779.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016734779.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
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DR RefSeq; XP_016734779.1; XM_016879290.1.
DR AlphaFoldDB; A0A1U8NAF8; -.
DR STRING; 3635.A0A1U8NAF8; -.
DR PaxDb; 3635-A0A1U8NAF8; -.
DR GeneID; 107945328; -.
DR KEGG; ghi:107945328; -.
DR OrthoDB; 1203965at2759; -.
DR Proteomes; UP000189702; Chromosome 5.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR GO; GO:0009755; P:hormone-mediated signaling pathway; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR025875; Leu-rich_rpt_4.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48056:SF45; BNAC07G31500D PROTEIN; 1.
DR PANTHER; PTHR48056; LRR RECEPTOR-LIKE SERINE/THREONINE-PROTEIN KINASE-RELATED; 1.
DR Pfam; PF00560; LRR_1; 8.
DR Pfam; PF12799; LRR_4; 1.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00369; LRR_TYP; 7.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000313|RefSeq:XP_016734779.1};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Receptor {ECO:0000313|RefSeq:XP_016734779.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000313|RefSeq:XP_016734779.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..1012
FT /note="non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010588042"
FT TRANSMEM 640..659
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 692..965
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 966..1012
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1012 AA; 110601 MW; 14D0F8605491B5F2 CRC64;
MSWLLCLLLF LLLHISHCSA ARTVSEFQAL LAVKSSITDD PQSYLSNWNA TTPLCSFTGV
TCDYTGRHVT SLNLSYFNLS GTLSPSFSHL RFLQNFSLAA NQLYGPIPTE LAALSALRYF
NLSNNVFNGS FPTQLSQLKN LQVLDLYNNN MTGDLPISVT DLPNLRHLHL GGNFFTGQIP
ASYGRWEHLE YLAVSGNELG GRIPPEIGNL KKLKELYIGY YNSFEGGLPP EIGNLSELVR
FDAANCMLSG EIPPEIGKLQ KLDTLFLQVN ALSGSLTPEL GTLESLKSMD LSNNMLAGEI
PESFADLKNL TLLNLFRNKL HGQIPEFIGE LPELEVLQLW ENNFTGNIPQ TLGSNRKLQL
LDLSSNKLTG TLPPDMCSGN TLHTLITLGN FLFGSIPESL GKCESLSRIR MGENFLNGSI
PKGLFGLPKL TQVELQDNYL TGEFPVTDSS ISLNLGQISL SNNRLSGPLP ATVGNFSGVQ
KLLLDGNKFS GPIPAEIGNL QQLSKMDFSH NKFSGRVAPG ISKCKLLTFV DLSRNELSGE
IPTEITGMRI LNYLNLSRNH LIGSIPSSIS TMQSLTSVDF SYNNLSGLVP STGQFSYFNY
TSFLGNPQLC GPYLGPCKDW VTNGTHQSHV KGGLSASLKL LLVIGLLVCS ILLAVAAIIK
ARSLKKASDS RAWKLTAFQR LDFTCDDVLD CLKEGNIIGK GGAGIVYKGI VPNGNQVAVK
RLPAMSLGSS HDHGFNAEIQ TLGKIRHRHI VRLLGFCSNH ETNLLVYEYM PNGSLGEVLH
GKKGGHLHWD TRYKIAVEAA KGLCYLHHDC SPLIVHRDVK SNNILLDSDF EAHVADFGLA
KFLQDSGTSE CMSAIAGSYG YIAPEYAYTL KVDEKSDVYS FGVVLLELVS GRKPVGEFGD
GVDIVQWVRK MTNSKKGVLK ILDPRLPSVP LHEVMHVFYV AMLCVEEQAV ERPTMREVVQ
ILTELPNASD SKQGDPTVTE SSHSPTSTLE SPNNATTKDP MPQSPTPDLL SI
//
