ID A0A1U8NAY1_GOSHI Unreviewed; 798 AA.
AC A0A1U8NAY1;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Phosphate transporter PHO1 homolog 3-like {ECO:0000313|RefSeq:XP_016736196.1};
GN Name=LOC107946403 {ECO:0000313|RefSeq:XP_016736196.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016736196.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016736196.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016736196.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: May transport inorganic phosphate (Pi).
CC {ECO:0000256|ARBA:ARBA00043939}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SYG1 (TC 2.A.94) family.
CC {ECO:0000256|ARBA:ARBA00009665}.
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DR RefSeq; XP_016736196.1; XM_016880707.1.
DR AlphaFoldDB; A0A1U8NAY1; -.
DR STRING; 3635.A0A1U8NAY1; -.
DR PaxDb; 3635-A0A1U8NAY1; -.
DR GeneID; 107946403; -.
DR KEGG; ghi:107946403; -.
DR OrthoDB; 1331193at2759; -.
DR Proteomes; UP000189702; Chromosome 5.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005802; C:trans-Golgi network; IBA:GO_Central.
DR GO; GO:0000822; F:inositol hexakisphosphate binding; IBA:GO_Central.
DR GO; GO:0015114; F:phosphate ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0016036; P:cellular response to phosphate starvation; IBA:GO_Central.
DR GO; GO:0006817; P:phosphate ion transport; IBA:GO_Central.
DR CDD; cd14476; SPX_PHO1_like; 1.
DR InterPro; IPR004342; EXS_C.
DR InterPro; IPR034092; PHO1_SPX.
DR InterPro; IPR004331; SPX_dom.
DR PANTHER; PTHR10783:SF140; SPX DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10783; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED; 1.
DR Pfam; PF03124; EXS; 1.
DR Pfam; PF03105; SPX; 1.
DR PROSITE; PS51380; EXS; 1.
DR PROSITE; PS51382; SPX; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphate transport {ECO:0000256|ARBA:ARBA00022592};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 394..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 436..457
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 477..498
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 518..537
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 544..561
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 606..623
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 643..660
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 666..692
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 713..733
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..343
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT DOMAIN 602..796
FT /note="EXS"
FT /evidence="ECO:0000259|PROSITE:PS51380"
FT REGION 210..244
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 210..232
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 798 AA; 92648 MW; 942559CFF31ED56E CRC64;
MKFGKEFASQ MVPEWQGAYM DYDYLKTLLK DIHTFNQRTK PQSIPHGLKR SLSMYRAFSG
LLIHRHSQHP PTSPPSPDVE EQPILVNSVN RNGSHKVETT FLMQGDKGGE YELVYFRRLD
DEFNKVDKFY KSKVAEVTQE AEVLNKQMDA LIAFRIKVEN PHGWSWQDRS GDLTRLASDV
ATSTATLAAT IPAGARASGR RSVEHMEIIE EGPSVHDESD EDKKDTVNKE SGEQNIEKPV
GSKFKKHKPA PLQILDRVKM NNTLATPRST IKVFLNAPKQ SDLKFDRENL KRVENKLKRA
FVEFYQKLLL LKSYSFLNTL AFSKIMKKYD KIASRNASES YMNMVDSSYL GSSEEVTKLM
ERVEATFIKH FANSNRSKGM NVLRPKARKQ RHTTTFYTGF FAGCTAALII ALILIIRARH
ILGHDGTDQY METMFPLYSL FGFIVLHMVM YAGNVYFWRR YRVNYAFIFG FKQGTELGYR
EVLLVSFGLA VMSLGSVLSN LDMEMDPKTN DYKAFTEIIP LILVVVVFII LFFPFNILYR
SSRFFFLTCL FHSILAPLYK VRLPDFFLAD QLTSQVQAFR SLEFYVCYYG WGDFRHRENS
CKTNDVFNTF SFIVAVIPFW SRLLQCLRRF FEEKDTLQGY NGVKYFITIV ALCLRTAYSL
NKGLGWEILA LVFSVAAAIV GTYWDLVYDW GLLQRHSRNR WLRDRLLVPR KSVYFGAMVL
NVLLRFAWLQ TVFNFKIFDL HRQTVTTIVA SLEIIRRGMW NFFRLENEHL NNVGKYRAFK
SVPLPFNYDE DEDEDKNE
//
