ID A0A1U8NCQ7_GOSHI Unreviewed; 351 AA.
AC A0A1U8NCQ7;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Alkylated DNA repair protein alkB homolog 8-like {ECO:0000313|RefSeq:XP_016736800.1};
GN Name=LOC107946842 {ECO:0000313|RefSeq:XP_016736800.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016736800.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016736800.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016736800.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the alkB family.
CC {ECO:0000256|ARBA:ARBA00007879}.
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DR RefSeq; XP_016736800.1; XM_016881311.1.
DR AlphaFoldDB; A0A1U8NCQ7; -.
DR STRING; 3635.A0A1U8NCQ7; -.
DR PaxDb; 3635-A0A1U8NCQ7; -.
DR GeneID; 107946842; -.
DR KEGG; ghi:107946842; -.
DR OrthoDB; 147254at2759; -.
DR Proteomes; UP000189702; Chromosome 5.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0070988; P:demethylation; IEA:InterPro.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 2.60.120.590; Alpha-ketoglutarate-dependent dioxygenase AlkB-like; 1.
DR InterPro; IPR027450; AlkB-like.
DR InterPro; IPR037151; AlkB-like_sf.
DR InterPro; IPR032857; ALKBH4.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR12463:SF1; FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12463; OXYGENASE-RELATED; 1.
DR Pfam; PF13532; 2OG-FeII_Oxy_2; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
DR PROSITE; PS50102; RRM; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 18..96
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 198..324
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51471"
SQ SEQUENCE 351 AA; 38687 MW; 829BFF176109655E CRC64;
MVMPRFVRPK EGDSESSPNL YVANCGPAVG LSFDTIASAF SSFGEVKGVY AADESGARVI
VSFLEPASAH SAFIALNGRP CPHLGGRSLH IRHSILQPPS SRGMASVPVS LNASDLNIPG
LYLFHDFISA VEEEQLLQAV DTGSWISLSK RRVQHYGYKF CYDTRNVDTK QHLGALPSFV
SFILERISLS PDIPEKLDLD QLTVNEYPPG VGLSPHIDTH SAFEGLIFSL SLAGPCIMEF
RRYTAGSWAP KTASISDTEV ENPNSCSEVS RKAVYLPPRS MLLLSGEARC AWHHYIPHHK
IDKVNETMIR RGSRRVSFTF RKVRRGPCQC EFPQYCDSQS QTRGGGFCCA T
//
