ID A0A1U8NDV4_GOSHI Unreviewed; 525 AA.
AC A0A1U8NDV4;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Uncharacterized protein LOC107947125 {ECO:0000313|RefSeq:XP_016737176.1};
GN Name=LOC107947125 {ECO:0000313|RefSeq:XP_016737176.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016737176.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016737176.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016737176.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-
CC deoxyribonucleoside 5'-triphosphate + ADP; Xref=Rhea:RHEA:44640,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61560, ChEBI:CHEBI:73316,
CC ChEBI:CHEBI:456216; EC=2.7.4.6;
CC Evidence={ECO:0000256|ARBA:ARBA00000082};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-
CC triphosphate + ADP; Xref=Rhea:RHEA:18113, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:57930, ChEBI:CHEBI:61557, ChEBI:CHEBI:456216; EC=2.7.4.6;
CC Evidence={ECO:0000256|ARBA:ARBA00000937};
CC -!- SIMILARITY: Belongs to the NDK family. {ECO:0000256|RuleBase:RU004011}.
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DR RefSeq; XP_016737176.1; XM_016881687.1.
DR AlphaFoldDB; A0A1U8NDV4; -.
DR STRING; 3635.A0A1U8NDV4; -.
DR PaxDb; 3635-A0A1U8NDV4; -.
DR GeneID; 107947125; -.
DR KEGG; ghi:107947125; -.
DR OrthoDB; 1212936at2759; -.
DR Proteomes; UP000189702; Chromosome 5.
DR GO; GO:0004550; F:nucleoside diphosphate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0006241; P:CTP biosynthetic process; IEA:InterPro.
DR GO; GO:0006183; P:GTP biosynthetic process; IEA:InterPro.
DR GO; GO:0006228; P:UTP biosynthetic process; IEA:InterPro.
DR CDD; cd04413; NDPk_I; 1.
DR CDD; cd00821; PH; 1.
DR Gene3D; 3.30.70.141; Nucleoside diphosphate kinase-like domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR HAMAP; MF_00451; NDP_kinase; 1.
DR InterPro; IPR034907; NDK-like_dom.
DR InterPro; IPR036850; NDK-like_dom_sf.
DR InterPro; IPR001564; Nucleoside_diP_kinase.
DR InterPro; IPR023005; Nucleoside_diP_kinase_AS.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR34837; OS05G0595500 PROTEIN; 1.
DR PANTHER; PTHR34837:SF2; OS05G0595500 PROTEIN; 1.
DR Pfam; PF00334; NDK; 1.
DR PRINTS; PR01243; NUCDPKINASE.
DR SMART; SM00562; NDK; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF54919; Nucleoside diphosphate kinase, NDK; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS00469; NDP_KINASES; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702}.
FT DOMAIN 175..290
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 77..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 138..165
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 525 AA; 58834 MW; 6D10605CC276303A CRC64;
MVRRGVETEH KILFPLVNTE KERSFFLFKS NHCRACPLFF DSCCLYKFKR STFLEYNFMD
DGFGKIKVIP DHFQVSTPPS EDSLQNRSSP DSQPSTGNSS RSRSSLWSRR KLRRAAFMLN
LFSLRGLPWS GADGQEKVQL TAAELESLRS ELADIEEREA HLKAQLEHID EILRSARLSG
YLYIRSRWTA LPGEPAPIDD IDVDDWLPRF VVLHGQCIFF YLCSTDLSPQ DSTLLSDVVE
VGPLPNFIRE GEGTQYSFYI LTRQGLRYEC SHVSEVQVDT WLSALRTDCN SQIFRSASRA
ARSLLSASKA SRFYSEGRAV AAAAAVSLGG KVPLLASAYG STASANASRA WLSGVFALPV
AAYMLQEQEV HAAEMERTFI AIKPDGVQRG LISEIISRFE RKGFKLVAIK LVVPSKEFAQ
KHYDDLKERP FFNGLCEFLS SGPVLAMVWE GEGVIKYGRK LIGATDPQKS EPGTIRGDLA
VVVGRNIIHG SDGPETAKHE INLWFKPQEL VNYTSNAEKW VYGNN
//
