ID A0A1U8NH64_GOSHI Unreviewed; 870 AA.
AC A0A1U8NH64;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Importin subunit beta-1 {ECO:0000313|RefSeq:XP_016737293.1};
GN Name=LOC107947228 {ECO:0000313|RefSeq:XP_016737293.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016737293.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016737293.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016737293.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the importin beta family. Importin beta-1
CC subfamily. {ECO:0000256|ARBA:ARBA00010907}.
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DR RefSeq; XP_016737293.1; XM_016881804.1.
DR AlphaFoldDB; A0A1U8NH64; -.
DR STRING; 3635.A0A1U8NH64; -.
DR PaxDb; 3635-A0A1U8NH64; -.
DR OrthoDB; 124901at2759; -.
DR Proteomes; UP000189702; Chromosome 5.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0061608; F:nuclear import signal receptor activity; IBA:GO_Central.
DR GO; GO:0008139; F:nuclear localization sequence binding; IBA:GO_Central.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR040122; Importin_beta.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR PANTHER; PTHR10527:SF1; IMPORTIN SUBUNIT BETA-1; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR Pfam; PF03810; IBN_N; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000189702}.
FT DOMAIN 23..103
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
SQ SEQUENCE 870 AA; 96067 MW; 77F7B6E253BDB921 CRC64;
MAMEVTQVLL NAQSIDGAVR KNAEDSLKQF QEQNLPVFLV SLSGELANEE KPVETRKLAG
LVLKNALDAK EQHRKFELVQ RWLSLDGNAK SQIKACLLTT LTSPVSDARS TASQVIAKVA
GIELPHKQWP ELIGSLLSNV HQLPAQAKQA TLETLGYLCE EVSPDVIDQD QVNKILTAVV
QGMSSSEGNT DVRLAATRAL YNALGFAQAN FSNDMERDYI MRVVCEATLS PEVRIRQAAF
ECLVSISSTY YEKLAPYIQD IFNITAKAVR EDEEPVALQA IEFWSSICDE EIDILEEYGG
DFTGDSDIPC FYFIKQALPA LVPMLLETLL KQEEDQDQDE GAWNIAMAGG TCLGLVARTV
GDDIVPLVVP FIEENISKPD WRQREAATYA FGSILEGPSP EKLIPLVNVA LTFMLSALTK
DPNSHVKDTT AWTLGRIFEF LHGSVVDSPI ISQANCQQII TVLLQSMKDT PNVAEKACGA
LYFLAQGYEE MGPSSPLTPF FQEIVQSLLT VTHREDAGES RLRTAAYETL NEVVRCSTDE
TAPLVLQLVP VIMMELHNTL EGQKLSSDER EKQSELQGLL CGCLQVIIQK LGASEPTKYV
FMQYADQIMG LFLWVFACRS ATVHEEAMLA IGALAYATGA DFAKYMPEFY RYLEMGLQNF
EEYQVCAVTV GVVGDISRAL EEKIVPYCDG IMTQLLKNLS SNQLHRSVKP PIFSCFGDIA
LAVGEYFEKY LMWAMSALQS AAELSTHIAG DDELVEYTNS LRNGILEAYS GIFQGFKNSP
KTQLLIPYAP HILQFLDGIY MEKDMDDVVM KTAIGVLGDL ADTLGSHAGS MIQQSVSSKD
FLNECLSSED LMIKESAEWA KLAISRAISV
//
